Fig. 6
From: Knockdown of circSMAD2 inhibits the tumorigenesis of gallbladder cancer through binding with eIF4A3
Knockdown of circSMAD2 significantly inhibited the tumor growth of GBC in vivo. (A) At the end of study, mice were sacrificed for the collection of tumor tissues, and then tissues were pictured and weighted. (B) The volume of tissues was tested weekly. (C) The level of circSMAD2 in tumor tissues of mice was detected by RT-qPCR. (D) The protein levels of SMAD2 and cleaved caspase 3 in tumor tissues of mice were investigated by western blot. The relative expressions were quantified by normalizing to β-actin. **P < 0.01 compared to control