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Table 1 Patients´ characteristics

From: Relevance of the time interval between surgery and adjuvant radio (chemo) therapy in HPV-negative and advanced head and neck carcinoma of unknown primary (CUP)

 

All patients

(n = 59)

Early treatment group (n = 30)

Delayed treatment group (n = 29)

Statistical comparison

Gender (n, %)

 Male

49 (83.0%)

26 (86.7%)

23 (79.3%)

X2(1) = 0.57, p = 0.451

 Female

10 (17.0%)

4 (13.3%)

6 (20.7%)

 

Age (mean years ± SD)

60.76 ± 10.42

58.43 ± 9.39

63.17 ± 11.03

t(57) = 1.97, p = 0.054

Nodal stage (n, %)

 pN1

5 (8.5%)

4 (13.3%)

1 (3.5%)

 

 pN2a

5 (8.5%)

3 (10.0%)

2 (6.9%)

 

 pN2b

9 (15.2%)

4 (13.3%)

5 (17.2%)

X2(3) = 2.20, p = 0.533

 pN2c

0 (0%)

0 (0%)

0 (0%)

 

 pN3a

0 (0%)

0 (0%)

0 (0%)

 

 pN3b

40 (67.8%)

19 (63.4%)

21 (72.4%)

 

UICC stage (n, %)

 III

4 (6.8%)

3 (10.0%)

1 (3.5%)

X2(2) = 1.15, p = 0.563

 IVA

15 (25.4%)

8 (26.7%)

7 (24.1%)

 

 IVB

40 (67.8%)

19 (63.3%)

21 (72.4%)

 

Extranodal extension (n, %)

 Yes

42 (71,19%)

20 (66.7%)

22 (75.9%)

X2(1) = 0.61, p = 0.436

 No

17 (28.81%)

10 (33.3%)

7 (24.1%)

 

Noxious agents

 Smoking

42 (71.2%)

22 (73.3%)

20 (69.0%)

X2(1) = 0.14, p = 0.711

 Alcohol

41 (69.5%)

19 (63.3%)

22 (75.9%)

X2(1) = 3.78, p = 0.151

ASA-Score

 1

5 (8.5%)

3 (10.0%)

2 (6.9%)

X2(2) 0.35, p = 0.841

 2

47 (79.7%)

23 (76.7%)

24 (82.7%)

 

 3

7 (11.8%)

4 (13.3%)

3 (10.3%)

 
  1. Abbreviations: Early treatment group = adjuvant treatment was implemented in less than 55 d after surgery; Delayed treatment group = adjuvant treatment was implemented within or later than 55 d following surgery; SD standard deviation; UICC International Union Against Cancer; ASA American Society of Anesthesiologists