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Table 2 Result of univariate analyses for short-term postoperative tumour response

From: Intraarterial contrast-enhanced ultrasound to predict the short-term tumour response of hepatocellular carcinoma to Transarterial chemoembolization with Lipiodol

Characteristics

Complete remission (n = 16)

non-complete remission (n = 28)

P value

Patients

 Age(y)a

61.69 (9.58)

56.89 (11.92)

0.18

Sex

 Male

14 (31.82)

27 (61.36)

0.61

 Female

2 (4.55)

1 (2.27)

 

Hepatitis background

 Hepatitis B

14 (31.82)

24 (54.55)

0.41

 Hepatitis’s C

1 (2.27)

2 (4.55)

 

 Hepatitis B + C

1 (2.27)

0 (0)

 

 No hepatitis

0 (0)

2 (4.55)

 

Lesions

CR (n = 24)

Non-CR (n = 37)

 

 Diameter (cm) a

2.50 (1.08)

4.63 (3.16)

<0.001

Location

 Left lobe

5 (8.20)

8 (13.11)

0.94

 Right lobe

19 (31.15)

29 (47.54)

 

Echo in B-mode ultrasound

 Hypoechoic

10 (16.39)

14 (22.95)

0.85

 Isoechoic

6 (9.84)

8 (13.11)

 

 Hyperechoic

8 (13.11)

15 (24.59)

 

Preoperative IA-CEUS

HA-CEUS

 Corona enhancement in late phase

  Yes

22 (36.07)

27 (44.26)

0.14

  No

2 (3.28)

10 (16.39)

 

  Corona thickness (cm) a

0.56 (0.23)

0.67 (0.61)

0.31

 Non-enhancing area in SMA-CEUS

  larger than 2D-US

8 (13.11)

22 (36.07)

0.046

  No larger than 2D-US

16 (26.23)

15 (24.59)

 

Postoperative HA-CEUS

 Intratumoural enhancement

  Yes

12 (19.67)

31 (50.82)

0.005

  No

12 (19.67)

6 (9.84)

 

 Corona enhancement in late phase

  Yes

4 (6.56)

21 (34.43)

0.004

  No

20 (32.79)

16 (26.23)

 

  Corona thickness (cm)b

0.00 (0.00, 0.00)

0.30 (0.00, 0.70)

0.003

  Corona thickness decrease (cm) b

0.50 (0.40, 0.70)

0.20 (0.00, 0.40)

0.006

  1. Note. — Data in parentheses are percentages unless otherwise indicated. CEUS contrast-enhanced ultrasound, IA-CEUS intra-arterial contrast-enhanced ultrasound, HA-CEUS hepatic artery contrast-enhanced ultrasound, SMA-CEUS superior mesenteric artery contrast-enhanced ultrasound. a: Data in parentheses are standard deviations. b: Data are median, with interquartile range in parentheses