Skip to main content

Table 4 Risk factors for delayed CINV

From: Pooled analysis of combination antiemetic therapy for chemotherapy-induced nausea and vomiting in patients with colorectal cancer treated with oxaliplatin-based chemotherapy of moderate emetic risk

 

Delayed nausea

Delayed vomiting

 

Univariate

Multivariate

Univariate

Multivariate

 

OR (95%CI)

p-value

OR (95%CI)

p-value

OR (95%CI)

p-value

OR (95%CI)

p-value

Age: < 65 vs. ≥ 65 years

1.678 (0.903–3.116)

0.1014

  

1.976 (0.614–6.354)

0.2533

  

Sex: female vs. male

1.909 (1.288–2.829)

0.0013

1.918 (1.292–2.848)

0.0012

2.636 (1.378–5.044)

0.0034

2.735 (1.410–5.304)

0.0029

Motion sickness: yes vs. no

1.921 (1.161–3.180)

0.0111

  

2.027 (0.993–4.138)

0.0524

  

Drinking habit: yes vs. no

1.361 (0.843–2.196)

0.2069

  

1.712 (0.724–4.051)

0.2208

  

Regimen: FOLFOX vs. XELOX

1.067 (0.713–1.597)

0.7529

  

1.616 (0.863–3.028)

0.1339

  

2 antiemetics vs. 3 antiemetics

1.474 (0.998–2.176)

0.0514

1.485 (1.000–2.204)

0.0498

4.429 (2.074–9.460)

0.0001

4.551 (2.116–9.785)

0.0001