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Table 1 Population and tumor characteristics

From: TFEB, SIRT1, CARM1, Beclin-1 expression and PITX2 methylation in breast cancer chemoresistance: a retrospective study

Age (years)

55 (48–65)

BMI (kg/m2)

25 (22–29)

Tobacco smoke

12.5% (12/96)

Family history

42.22% (19/45)

EP use

31.82% (7/22)

Post-menopausal status

71.32% (97/136)

Definitive breast surgery

 Conservative

31.62% (43/136)

 Mastectomy

68.38% (93/136)

 Axilla surgery: definitive CALND

69.12% (94/136)

Non-surgical therapy

 Neoadiuvant chemoterapy

8.82% (12/136)

 Radiotherapy

56.62% (77/136)

vAdiuvant chemoterapy

99.26% (135/136)

 Anti-hormonal therapy

74.26% (101/136)

Histology

 Invasive ductal carcinoma

80.88% (110/136)

 Invasive lobular carcinoma

11.03% (15/136)

 Invasive ductal and lobular carcinoma

6.62% (9/136)

 Other invasive cancers

1.47% (2/136)

Molecular types

 Luminal A

18.38% (25/136)

 Luminal B

28.68% (39/136)

 Luminal HER2

8.09% (11/136)

 HER2 enriched

11.03% (15/136)

 Basal-like

13.97% (19/136)

 Not described

19.85% (27/136)

Other tumor caracteristics

 Mib-1/Ki-67 (median percentage)

30 (10–70)

 Mib-1/Ki-67 (> 20%)

55.77% (58/104)

 Comedo-like nescrosis

13.24% (18/136)

 Multifacality/multicentricity

24.26% (33/136)

 Extended in situ component

21.32% (29/136)

 Perivascular invasion

40.44% (55/136)

Lymph node characteristics

 Micro-metastatic lymph nodes

5.88% (8/136)

 Extracapsular invasion

25.74% (35/136)

 Axilla lymph node bunching

7.35% (10/136)

  1. Acronyms: BMI body mass index, SLNB sentinel lymph node biopsy, CALND complete
  2. axilla lymph node dissection