Fig. 2

Kaplan-Meier survival curves and p-values refers to Log-rank tests. A Curve based on TFEB expression (high expression consists in an H-score greater than the distribution median [> 185] and low expression in an H-score lower or equal to the distribution median) (p < 0.05). B Analysis based on CARM1 expression (i.e., high with an H-score higher than the median distribution [> 85] or low, i.e., with an H-score lower than or equal to the distribution median) (p = 0.156). C Analysis of survival based on SIRT1 expression (i.e., high with an H-score higher than the median distribution [190] or low, i.e., with an H-score lower than or equal to the distribution median) (p = 0.322). D Analysis of survival based on the expression of Beclin-1 (i.e., high with an H-score higher than the median distribution [> 90] or low, i.e., with an H-score lower than or equal to the distribution median) (p < 0.05). E Analysis of survival based on the expression of SIRT1 with a different cut-off (i.e., high with an H-score higher than the first quartile (*) of the distribution [> 100] or low, i.e., with an H-score lower than or equal to the first quartile of the distribution) (p < 0.05). F Subgroup analysis of survival (luminal A, luminal B, and luminal Her sub-types) based on the expression of SIRT1 (i.e., high with an H-score higher than the first quartile (*) of the distribution [132] or low, i.e., with an H-score lower than or equal to the first quartile of the distribution) (p = 0.055). Panel G: Subgroup analysis of survival (Her enriched and Basal-like sub-types) based on the expression of SIRT1 (i.e., high with an H-score higher than the first quartile (*) of the distribution [132] or low, i.e., with an H-score lower than or equal to the first quartile of the distribution) (p = 0.294)