Table 3 DAVID analysis functional annotation, gene ontology, 6-h and 12-h FX-9 exposure
GO.biological processes | 6-h | 12-h | ||
|---|---|---|---|---|
DEGs | FDR | DEGs | FDR | |
inflammatory response | 18 | 1.30E-04 | 12 | 2.70E-02 |
angiogenesis | 14 | 1.30E-04 | 13 | 1.70E-04 |
positive regulation of cell migration | 12 | 4.80E-04 | 11 | 6.00E-04 |
positive regulation of angiogenesis | 10 | 4.80E-04 | 9 | 8.40E-04 |
I-kappaB kinase/NF-kappaB signaling | 7 | 5.30E-03 | ||
negative regulation of cell proliferation | 15 | 5.30E-03 | ||
positive regulation of NF-kappaB transcription factor activity | 9 | 7.40E-03 | ||
positive regulation of transcription from RNA polymerase II promoter | 24 | 8.00E-03 | ||
extracellular matrix organization | 10 | 1.40E-02 | 10 | 4.80E-03 |
negative regulation of apoptotic process | 15 | 1.40E-02 | 14 | 9.40E-03 |
cell adhesion | 15 | 1.40E-02 | ||
positive regulation of nitric-oxide synthase biosynthetic process | 4 | 2.50E-02 | ||
positive regulation of ERK1 and ERK2 cascade | 9 | 2.70E-02 | ||
G1/S transition of mitotic cell cycle | 9 | 6.00E-04 | ||
positive regulation of endothelial cell proliferation | 6 | 2.70E-02 | ||