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Table 1 Hypothesized mechanisms of CRF and corresponding dimensions (adapted from McNeely and Courneya 2010)

From: Building a biopsychosocial model of cancer-related fatigue: the BIOCARE FActory cohort study protocol

Physiological Biological Psychological Behavioral Social
• Muscular strength
• Muscular endurance
• Cardiopulmonary fitness
• Body composition
• Inflammatory response
• Metabolic function
• Endocrine function
• Immune function
• Anxiety
• Depression
• Distress
• Cognition
• Sleep quality and quantity
• Appetite
• Social interactions
• Positive reinforcement