Fig. 3
From: LncRNA LINC00342 promotes gastric cancer progression by targeting the miR-545-5p/CNPY2 axis
LINC00342 served as a sponge of miR-545-5p. A and B The putative binding sites between LINC00342 and miR-545-5p was predicted by StarBase, and the relative luciferase activity of LINC00342 WT/MT was detected by dual luciferase reporter system. C AGS cells were transfected with two siRNAs targeting LINC00342, and the expression of miR-545-5p was evaluated by qRT-PCR. D and E AGS cells were transfected with miR-545-5p mimics/NC mimics, or miR-545-5p inhibitor/NC inhibitor. The expression of miR-545-5p (D) and LINC00342 (E) was evaluated by qRT-PCR. (F) The expression of miR-545-5p in GC tissues (n = 30) and matched adjacent tissues (n = 30) was measured by qRT-PCR. G The correlation between the levels of LINC00342 and miR-545-5p was evaluated by Spearman’s correlation analysis. ** p < 0.01 vs NC mimics/si-NC; ## p < 0.01 vs NC inhibitor