BMC Cancer

Table 1 Association between C3 and FN1 expression and demographic and clinicopathological parameters of patients with ccRCC in the TCGA profile

From: Identification of C3 and FN1 as potential biomarkers associated with progression and prognosis for clear cell renal cell carcinoma

Parameter		C3 expression				FN1 expression
Parameter		High (n = 361)	Low (n = 171)	χ²	p-value	High (n = 190)	Low (n = 342)	χ²	p-value
Age (mean ± SD)		60.96 ± 12.46	59.80 ± 11.43		0.304	59.28 ± 12.75	61.31 ± 11.74		0.065
Gender	Female	118	68	2.557	0.110	49	137	10.937	0.001
Gender	Male	243	103	2.557	0.110	141	205	10.937	0.001
Clinical stage	I/II	202	121	11.011	0.001	104	219	3.872	0.049
	III/IV	158	49			84	123
	Unknown	1	1			2	0
Pathologic T	T1,T2	215	126	10.064	0.002	108	233	6.761	0.009
	T3,T4	146	45			82	109
	Unknown	0	0			0	0
Pathologic N	N0	168	72		0.046	85	155	2.802	0.094
	N1	15	1			9	7
	Nx + null	178	98			96	180
Pathologic M	M0	284	138	3.894	0.048	152	270	0.577	0.448
	M1	62	17			32	47
	Mx + null	15	16			6	25
Recurrence status	No	71	50	0.533	0.466	33	88	0.036	0.850
	Yes	16	8			7	17
	Null	274	113			150	237
Living status	Living	34	252	14.467	<0.001	114	243	6.760	0.009
Living status	Dead	15	85	14.467	<0.001	76	99	6.760	0.009

Abbreviations: ccRCC clear cell Renal Cell Carcinoma, TCGA The Cancer Genome Atlas, T primary tumour, N regional lymph node, Nx regional lymph nodes are unknown, M distant metastasis, Mx distant metastasis is unknown; Significant associations are shown in boldface in the p-value column (p-value < 0.05)

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