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Table 1 Association between C3 and FN1 expression and demographic and clinicopathological parameters of patients with ccRCC in the TCGA profile

From: Identification of C3 and FN1 as potential biomarkers associated with progression and prognosis for clear cell renal cell carcinoma

Parameter   C3 expression FN1 expression
High (n = 361) Low (n = 171) χ2 p-value High (n = 190) Low (n = 342) χ2 p-value
Age (mean ± SD)   60.96 ± 12.46 59.80 ± 11.43   0.304 59.28 ± 12.75 61.31 ± 11.74   0.065
Gender Female 118 68 2.557 0.110 49 137 10.937 0.001
Male 243 103 141 205
Clinical stage I/II 202 121 11.011 0.001 104 219 3.872 0.049
III/IV 158 49 84 123
Unknown 1 1 2 0
Pathologic T T1,T2 215 126 10.064 0.002 108 233 6.761 0.009
T3,T4 146 45 82 109
Unknown 0 0 0 0
Pathologic N N0 168 72   0.046 85 155 2.802 0.094
N1 15 1 9 7
Nx + null 178 98 96 180
Pathologic M M0 284 138 3.894 0.048 152 270 0.577 0.448
M1 62 17 32 47
Mx + null 15 16 6 25
Recurrence status No 71 50 0.533 0.466 33 88 0.036 0.850
Yes 16 8 7 17
Null 274 113 150 237
Living status Living 34 252 14.467 <0.001 114 243 6.760 0.009
Dead 15 85 76 99
  1. Abbreviations: ccRCC clear cell Renal Cell Carcinoma, TCGA The Cancer Genome Atlas, T primary tumour, N regional lymph node, Nx regional lymph nodes are unknown, M distant metastasis, Mx distant metastasis is unknown; Significant associations are shown in boldface in the p-value column (p-value < 0.05)