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Table 5 Association of BRAFV600E and TERT overexpression with disease aggressiveness in 40 patients with thyroid cancer

From: Utility of droplet digital polymerase chain reaction for TERT and BRAF mutational profiling of thyroid nodules

Pathology

BRAFV600E

P-value

TERT

P-value

N = 20

N = 10

Tumor type

2

0.69

4

< 0.001

 ATC vs WDTC

Stage

8

0.626

7

0.025

  T3/4 vs T1/2

19

< 0.001

9

0.079

  N1 vs N0

    

LVI or PNI present

10

0.047

3

0.702

Extrathyroidal extension

8

0.311

6

0.032

Multifocal

11

0.008

4

0.702

Recurrence

4

0.035

1

1

  1. ATC anaplastic thyroid cancer; LVI lymphovascular invasion; PNI perineural invasion; WDTC well-differentiated thyroid cancer
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BMC Cancer

ISSN: 1471-2407

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