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Table 1 Vital status at six-months, sociodemographic characteristics, smoking status, province of residence, body mass index, cancer surgery, histology, and TNM stage by multimorbidity status among lung cancer patients diagnosed between 2011 and 2012, in two population-based Spanish cancer registries: Girona and Granada (n = 1259 lung cancer patients and 581 deaths at six-months after cancer diagnosis)

From: The role of multimorbidity in short-term mortality of lung cancer patients in Spain: a population-based cohort study

Variable

Royal College of Surgeons-modified Charlson score

 

No comorbidity

One comorbidity

Two or more comorbidities

p-value

N (%)

N (%)

N (%)

 

Vital status at 6 months

   

0.001

 Alive

290 (42.8)

189 (27.9)

199 (29.4)

 

 Dead

196 (33.7)

164 (28.2)

221 (38.0)

 

Age at diagnosis, years

   

< 0.001

  < 60

179 (58.9)

77 (25.3)

48 (15.8)

 

 60–69

132 (39.4)

111 (33.1)

92 (27.5)

 

 70–79

110 (28.4)

113 (29.2)

164 (42.4)

 

  ≥ 80

65 (27.9)

52 (22.3)

116 (49.8)

 

Sex

   

< 0.001

 Male

355 (33.8)

321 (30.6)

374 (35.6)

 

 Female

131 (62.7)

32 (15.3)

46 (22.0)

 

Smoking status

   

< 0.001

 Current smoker

187 (41.3)

144 (31.8)

122 (26.9)

 

 Previous smoker

126 (25.2)

153 (30.5)

222 (44.3)

 

 Never smoked

65 (45.8)

37 (26.1)

40 (28.2)

 

Province

   

0.019

 Girona

216 (43.3)

133 (26.7)

150 (30.1)

 

 Granada

270 (35.5)

220 (29.0)

270 (35.5)

 

Body Mass Index (kg/m2)

   

< 0.001

 Healthy weight (< 25.0)

142 (45.8)

92 (29.7)

76 (24.5)

 

 Overweight (25.0–29.9)

99 (35.9)

90 (32.6)

87 (31.5)

 

 Obese (≥30)

33 (21.9)

45 (29.8)

73 (48.3)

 

Surgery

   

0.163

 Yes

81 (40.1)

63 (31.2)

58 (28.7)

 

 No

362 (35.8)

289 (28.6)

361 (35.7)

 

Histology

   

< 0.001

 ADE

176 (46.1)

101 (26.4)

105 (27.5)

 

 Others

134 (35.5)

99 (26.2)

145 (38.4)

 

 SCLC

73 (44.2)

44 (26.7)

48 (29.1)

 

 SQUA

103 (30.8)

109 (32.6)

122 (36.5)

 

TNM stage

   

0.014

 I

0 (0.0)

1 (20.0)

4 (80.0)

 

 II

67 (35.1)

61 (31.9)

63 (33.0)

 

 III

107 (30.7)

106 (30.4)

136 (39.0)

 

 IV

267 (40.5)

183 (27.8)

209 (31.7)

 
  1. Histology: ADE: adenocarcinoma; SCLC: small cell lung cancer; SQUA: Squamous carcinoma;
  2. Others: non-small cell lung cancer, large cell lung cancer, neuroendocrine lung cancer,
  3. and unspecified lung cancer. P-values based on Chi-square tests
  4. Missing values: BMI n (%) = 522 (41.5), Performance status n (%) = 229 (18.2),
  5. Smoking status n (%) = 163 (13.0), TNM stage n (%) = 55 (4.4), Surgery n (%) = 45 (3.6)