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Table 5 Normalized growth rate reduction of SNU-228 and SNU-267 cells at the highest concentrations used of the indicated anti-cancer drugs

From: Prospective pharmacological methodology for establishing and evaluating anti-cancer drug resistant cell lines

 

Sunitinib

Axitinib

Pazopanib

Sorafenib

Everolimus

Temsirolimus

SNU-228

Control

1.13

1.37

1.24

1.34

1.43

1.45

Resistant cells

0.93 (0.82)

1.02 (0.74)

1.06 (0.85)

1.18 (0.88)

1.23 (0.86)

1.23 (0.85)

Reversible

0.94 (0.83)

1.06 (0.77)

0.93 (0.75)

1.17 (0.87)

1.24 (0.87)

1.24 (0.86)

SNU-267

Control

1.17

1.38

1.42

1.36

1.33

1.35

Resistant cells

1.05 (0.90)

1.24 (0.90)

1.27 (0.89)

1.24 (0.91)

1.23 (0.92)

1.24 (0.92)

Reversible

1.01 (0.86)

1.22 (0.88)

1.27 (0.89)

1.23 (0.90)

1.19 (0.89)

1.23 (0.91)