First author | TP | FP | TN | FN | PPV, % | NPV, % | Sensitivity, % | Specificity, % | Accuracy, % | AUROC | 95%CI | Standard Error c |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Deep learning | ||||||||||||
 Per-patient | ||||||||||||
  Ding [12] | – | – | – | – | – | – | – | – | – | 0.920 | 0.876–0.964 | 0.0224 |
  Wang [11] | 40 | 4 | 58 | 5 | 90.9 | 92.1 | 88.9 | 93.5 | 91.6 | 0.912 c | 0.842–0.958 | 0.0296 |
  Glaser [25] a | – | – | – | – | – | – | – | – | – | 0.860 | – | – |
 Per-node | ||||||||||||
  Lu [28] | – | – | – | – | – | – | – | – | – | 0.912 | – | – |
  Li [29] | – | – | – | – | – | – | – | – | 94.4 | – | – | – |
Radiomics | ||||||||||||
 Per-patient | ||||||||||||
  Eresen [20] | 29 c | 6 c | 33 c | 10 c | 82.8 c | 76.7 c | 74.36 | 84.62 | 79.49 | 0.825 | 0.778–0.872 | 0.0240 |
  Li [21] | 69 c | 44 c | 128 c | 67 c | 61.06 | 65.64 | 50.74 | 74.42 | 63.96 | 0.650 | 0.583–0.713 | 0.0331 |
  Yang [22] | 13 c | 5 c | 21 c | 2 c | 73.2 c | 90.5 c | 85.0 | 82.0 | 83.0 | 0.780 | 0.630–0.920 | 0.0740 |
  Nakanishi [23] | – | – | – | – | – | – | – | – | – | 0.900 | 0.800–0.990 | 0.0485 |
  Zhou [24] | 24 c | 27 c | 74 c | 5 c | 47.1 | 93.7 | 82.8 | 73.3 | 75.4 | 0.818 | 0.731–0.905 | 0.0444 |
  Meng [26] | 46 c | 36 c | 47 c | 17 c | 56.1 c | 73.4 c | 73.0 | 56.6 | 63.7 | 0.697 | 0.612–0.781 | 0.0431 |
  Chen [30] | – | – | – | – | – | – | – | – | – | 0.857 | 0.726–0.989 | 0.0671 |
  Huang [31] | – | – | – | – | – | – | – | – | – | 0.788 | 0.779–0.797 | 0.0046 |
 Per-node | ||||||||||||
  Zhu [27] | 18 c | 21 c | 32 c | 1 c | 46.2 | 97.0 | 94.7 | 60.4 | 69.4 c | 0.812 | 0.703–0.895 | 0.0490 |
  Cai [32] | – | – | – | – | – | – | 89 | 82 | 88 | – | – | – |
  Tse [34] | – | – | – | – | – | – | – | – | 91.0 | – | – | – |
  Cui [33] | 111 c | 17 c | 78 c | 14 c | 86.7 c | 85.0 c | 89 | 82 | 88 | 0.855 c | 0.801–0.898 c | 0.0247 |
Radiologist | ||||||||||||
 Per-patient | ||||||||||||
  Li [21] d | 94 c | 63 c | 109 c | 42 c | 59.9 | 72.2 | 69.1 | 63.4 | 65.9 | 0.708 | 0.645–0.765 | 0.0306 |
  Eresen [20] | 33 c | 23 c | 16 c | 6 c | 58.9 c | 72.7 c | 84.6 | 41.0 | 62.8 | 0.772 | 0.718–0.825 | 0.0273 |
  Yang [22] | 41 | 41 | 43 | 14 | 50.0 | 75.4 | 74.6 | 51.2 | 60.4 | 0.629 c | 0.543–0.709 c | 0.0423 |
  Nakanishi [23] b | 71 | 0 | 147 | 29 | 100.0 | 83.5 | 71.0 | 100.0 | 88.3 c | 0.855 c | 0.805–0.896 c | 0.0232 |
  Zhou [24] b | 49 | 89 | 215 | 38 | 35.5 | 85.0 | 56.3 | 70.7 | 67.5 | 0.635 | 0.585–0.683 | 0.0250 |
  Meng [26] b | 88 c | 96 c | 124 c | 37 c | 47.8 c | 77.0 c | 55.9 | 70.4 | 61.3 | 0.632 c | 0.578–0.683 c | 0.0268 |
  Chen [30] | – | – | – | – | – | – | – | – | – | 0.671 | 0.511–0.831 | 0.0816 |
  Huang [31] | 58 c | 30 c | 69 c | 43 c | 65.9 c | 61.6 c | 57.4 c | 69.7 c | 63.5 c | 0.636 c | 0.565–0.702 c | 0.0349 |
 Per-node | ||||||||||||
  Cui [33] | 39 c | 101 c | 52 c | 36 c | 27.7 c | 59.1 c | 52 c | 34 c | 39.9 c | 0.430 c | 0.365–0.497 c | 0.0337 |