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Table 1 Characteristics of participants and endoscopy results of different esophageal lesions in Chinese high-risk population in 2017–2018

From: Risk factors for esophageal squamous cell carcinoma and its histological precursor lesions in China: a multicenter cross-sectional study

Factors

HGIN/ESCC

n = 437

LGIN

n = 1874

Esophagitis

n = 4890

Norma esophagus

n = 37,656

Total cohort

n = 44,857

P value

Gender, n(%)

     

< 0.001a

 Male

247 (56.5)

913 (48.7)

2290 (46.8)

15,590 (41.4)

19,040 (42.4)

 

 Female

190 (43.5)

961 (51.3)

2600 (53.2)

22,066 (58.6)

25,817 (57.6)

 

Age, mean (SD)

60.85 (5.80)

59.22 (6.25)

57.29 (6.85)

54.41 (7.26)

54.99 (7.30)

< 0.001b

Education, n(%)

     

< 0.001a

 No formal

81 (18.5)

368 (19.6)

744 (15.2)

5395 (14.3)

6588 (14.7)

 

 Formal

356 (81.5)

1506 (80.4)

4146 (84.8)

32,261 (85.7)

38,269 (85.3)

 

Occupation, n(%)

     

< 0.001a

 Non-farmer

86 (19.7)

382 (20.4)

1028 (21.0)

9347 (24.8)

10,843 (24.2)

 

 Farmer

351 (80.3)

1492 (79.6)

3862 (79.0)

28,309 (75.2)

34,014 (75.8)

 

BMI (kg/m2), n(%)

     

< 0.001a

 < 18.5

16 (3.7)

36 (1.9)

98 (2.0)

714 (1.9)

864 (1.9)

 

 18.5 to 23.9

229 (52.3)

914 (48.8)

2336 (47.8)

17,309 (46.0)

20,788 (46.3)

 

 24.0 to 27.9

159 (36.4)

742 (39.6)

1977 (40.4)

15,074 (40.0)

17,952 (40.1)

 

 ≥ 28.0

33 (7.6)

182 (9.7)

479 (9.8)

4559 (12.1)

5253 (11.7)

 
  1. Source: WHO tumor histological classification 2000. a = χ2 test; b = ANOVA test. Population recruited from five high-rate regions for upper gastrointestinal cancer in China, including Hebei, Henan, Shandong, Shanxi, and Gansu Provinces
  2. BMI body mass index (kg/m2), LGIN low-grade intraepithelial neoplasia, HGIN high-grade intraepithelial neoplasia, ESCC esophageal squamous cell carcinoma