Circulating MiR-1290 as a potential diagnostic and disease monitoring biomarker of human gastrointestinal tumors

BMC Cancer

Table 1 Clinical characteristics of patients included in the study

Groups	Control (n = 50)	Group 1 (n = 46)		Group 2 (n = 50)		Group 3 (n = 50)
Groups	Control (n = 50)	Pancreatic cancer	p value	Colorectal cancer	p value	Gastric cancer	p value
Age (year)			0.016*		0.102		0.151
< 65 y	34	20		26		27
≥ 65 y	16	26		24		23
Sex			0.084		0.105		0.841
Male	25	31		33		26
Female	25	15		17		24
BMI (kg/m²)			0.524		0.832		0.663
< 25	34	34		33		36
≥ 25	16	12		17		14
Smoke			0.167		0.021*		0.817
Yes	12	17		23		13
No	38	29		27		37
Alcohol			0.478		0.817		1.000
Yes	12	14		13		12
No	38	32		37		38
Hypertension			0.013*		0.047*		0.727
Yes	10	20		19		12
No	40	26		31		38
Diabetes			0.022*		1.000		0.629
Yes	5	13		5		4
No	45	33		45		46
CEA (ng/ml)			< 0.0001***		< 0.0001***		< 0.006**
< 5	50	30		33		43
≥ 5	0	16		17		7
CA199 (U/ml)			< 0.0001***		0.617		< 0.617
< 37	39	6		41		41
≥ 37	11	40		9		9
CA125 (U/ml)			< 0.0001***		0.169		< 0.137
< 35	46	24		49		41
≥ 35	4	22		1		9
CA242 (U/ml)			< 0.0001***		0.558		< 0.169
< 20	49	16		48		46
≥ 20	1	30		2		4
CA211 (ng/ml)			0.001**		0.307		0.092
< 5	49	34		47		45
≥ 5	1	12		3		5

ISSN: 1471-2407