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Table 1 Clinical characteristics of the patients with P. jirovecii pneumonia

From: Clinical characteristics and risk factors associated with Pneumocystis jirovecii infection in patients with solid tumors: study of thirteen-year medical records of a large cancer center

 

Patients with prolonged use of a moderate-to-high corticosteroid dose

(n = 6)

Patients without prolonged use of a moderate-to-high corticosteroid dose

(n = 14)

Total

(n = 20)

Age (years), median (range)

56 (46–76)

67 (40–90)

66 (40–90)

Cancer type, n (%)

 Lung cancer

1 (17)

5 (36)

6 (30)

 Breast cancer

1 (17)

2 (14)

3 (15)

 Esophageal cancer

0 (0)

2 (14)

2 (10)

 Pancreatic cancer

1 (17)

1 (7)

2 (10)

 Othersa

3 (50)

4 (29)

7 (35)

ALC, n (%)

  < 500

3 (50)

9 (64)

12 (60)

 500–999

2 (33)

4 (29)

6 (30)

  ≥ 1000

1 (17)

1 (7)

2 (10)

LDH (Units/L)

  < 250

1 (17)

2 (14)

3 (15)

 250–500

4 (67)

9 (64)

13 (65)

  > 500

1 (17)

3 (21)

4 (20)

BDG, median (range)

85.8 (19.8–522.1)

37.8 (16− > 600)

45 (16− > 600)

Main Radiologic findings, n (%)

 Ground glass opacities

5 (83)

13 (93)

18 (90)

 Otherb

1 (17)

1 (7)

2 (10)

  1. ALC Absolute lymphocyte count, LDH Lactate dehydrogenase, BDG Beta-D glucan, PSL Prednisolone
  2. a Rectal cancer, thyroid cancer, and inflammatory myofibroblastic tumor with single case each in patients with PSL ≥ 20 mg daily ≥4 weeks and ovarian cancer, renal cancer, laryngeal cancer, and hypopharyngeal cancer with a single case each in patients without PSL ≥ 20 mg daily ≥4 weeks
  3. b Examples of other findings were patchy, nodular, and focal consolidation