Fig. 3
From: Role of miR-182/PDCD4 axis in aggressive behavior of prostate cancer in the African Americans
Effect of miR-182 knockdown on apoptosis, cell cycle, and colony formation. A and B Stable inhibitor of miR-182 in DU-145 or MDA-PCa-2b (A) or LNCaP (B) knockdown cells by lentiviral vectors were evaluated by qPCR analysis using antisense miRNA. C Apoptosis assay in DU-145, LNCaP, and MDA-PCa-2b after the miR-182 knockdown. D and E Determination of cell cycle distribution after miR-182 knockdown of DU-145 (D), and MDA-PCa-2b (E), respectively, analyzed by propidium iodide staining by flow cytometry. F Clonogenic ability of DU-145 and MDA-PCa-2b after miR-182 knockdown determined by colony formation assay. Bar = ±SD. *, P < 0.05