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Table 2 Correlation between DFNA5 expression and clinical prognosis in head and neck squamous cell carcinoma with different clinicopathological factors using the Kaplan-Meier plotter

From: Prognostic role of DFNA5 in head and neck squamous cell carcinoma revealed by systematic expression analysis

Clinicopathological characteristics

OS survival

N

Hazard ratio

P-value

Gender:

Female

133

1.56 (0.95–2.55)

0.076

Male

366

1.43 (1.01–2.03)

0.041

Race:

White

426

0.35 (1.01–1.82)

0.044

black/African American

47

3.4 (1.3–8.91)

0.0084

1

25

7.29 (0.76–70.09)

0.044

Stage

2

69

0.45 (0.2–1)

0.043

3

78

1.55 (0.68–3.55)

0.29

4

259

1.75 (1.21–2.53)

0.0027

1

61

1.94 (0.8–4.7)

0.14

Grade:

2

298

1.29 (0.91–1.82)

0.15

3

119

2.25 (1.29–3.92)

0.0033

4

7

  

high

251

1.34 (0.91–1.98)

0.14

Mutation burden:

low

243

1.95 (1.29–2.97)

0.0014

enriched

243

1.7 (1.11–2.6)

0.013

Basophils:

decreased

254

1.22 (0.83–1.79)

0.3

enriched

238

2.07 (1.31–3.28)

0.0015

B-cells:

decreased

259

1.16 (0.77–1.73)

0.48

enriched

316

1.66 (1.16–2.37)

0.0048

CD4+ memory T-cells:

decreased

181

1.3 (0.84–2.01)

0.24

enriched

305

1.55 (1.05–2.27)

0.025

CD8+ T-cells:

decreased

192

1.62 (1.04–2.51)

0.03

enriched

215

1.55 (1.05–2.27)

0.025

Eosinophils:

decreased

282

1.53 (1.07–2.19)

0.02

enriched

205

1.49 (0.91–2.38)

0.12

Macrophages:

decreased

292

1.34 (0.93–1.94)

0.12

enriched

313

1.62 (1.15–2.27)

0.0053

Mesenchymal stem cells:

decreased

184

1.33 (0.85–2.07)

0.21

enriched

129

1.54 (0.94–2.52)

0.082

Natural killer T-cells:

decreased

368

1.36 (0.97–1.9)

0.077

enriched

322

1.43 (1.01–2.01)

0.04

Regulatory T-cells:

decreased

175

1.54 (0.95–2.48)

0.074

enriched

381

1.53 (1.11–2.11)

0.0082

Type 1 T-helper cells:

decreased

116

1.38 (0.8–2.39)

0.24

enriched

473

1.39 (1.04–1.85)

0.024

Type 2 T-helper cells:

decreased

24

4.84 (0.8–29.1)

0.057