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Table 3 Univariate analysis of relevant variables for OS and RFS

From: Association between preoperative serum albumin and prognosis in patients with adrenocortical carcinoma after primary resection: a retrospective study

Variables

RFS

OS

HR

95%CI 1(ref)

P-value

HR

95%CI 1(ref)

P-value

Gender

 Male

1.462

0.717–2.981

0.296

1.721

0.869–3.410

0.119

 Female

      

Age (years)

0.995

0.974–1.016

0.638

0.997

0.977–1.019

0.813

Hormonal secretion

 No

1.059

0.530–2.118

0.870

0.687

0.357–1.324

0.262

 Yes

      

Comorbidities

 No

1.082

0.542–2.162

0.823

0.759

0.394–1.461

0.409

 Yes

      

Diameter of tumor (cm)

  ≤ 8.8

1.027

0.517–2.039

0.940

1.345

0.717–2.525

0.356

  > 8.8

      

Tumor stage

 I

1.257

0.441–3.580

0.669

2.533

1.107–5.793

0.037

 II/III/IV

      

Modus operandi

 Laparoscopy

0.925

0.459–1.867

0.829

1.849

0.899–3.803

0.095

 Open

      

Post-recurrence adjuvant treatment

 No

   

1.118

0.572–2.185

0.745

 Yes

      

Recurrence

 No

   

1.769

0.922–3.394

0.086

 Yes

      

Albumin (g/L)

  ≤ 39

0.383

0.192–0.766

0.007

0.491

0.260–0.930

0.029

  > 39

      

Ki67 index (%)

1.024

0.999–1.050

0.059

1.034

1.011–1.057

0.004

Globulin (g/L)

0.989

0.929–1.054

0.741

0.994

0.940–1.052

0.846

Hemoglobin (g/L)

0.974

0.955–0.992

0.006

0.992

0.978–1.006

0.257

  1. Bold figures indicate statistical significance at P<0.05
  2. Abbreviations: OS overall survival, RFS recurrence-free survival, HR hazard ratio, CI confidence interval, 1 (ref) 1 degree of freedom