Table 1 Associations of sociodemographic and clinical characteristics with non-CSD
Variable | No. (%) | Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|---|---|
| Â | Total | Alive | CSD | Non-CSD | OR (95% CI) | p-value | OR (95% CI) | p-value |
Age, years | ||||||||
 20–39 (youngest) | 10,556 | 8332 (78.9) | 1302 (12.3) | 922 (8.7) | Reference |  | Reference |  |
 40–59 (older) | 4734 | 2758 (58.2) | 1011 (21.4) | 965 (20.4) | 2.68 (2.43–2.95) | < 0.001 | 3.05 (2.74–3.39) | < 0.001 |
  ≥ 60 (oldest) | 3228 | 443 (13.7) | 1455 (45.1) | 1330 (41.2) | 7.32 (6.64–8.07) | < 0.001 | 8.60 (7.70–9.62) | < 0.001 |
Period | ||||||||
 1983–1992 | 5022 | 2282 (45.4) | 1331 (26.5) | 1409 (28.1) | Reference |  | Reference |  |
 1993–2000 | 5743 | 3621 (63.0) | 1142 (19.9) | 980 (17.1) | 0.53 (0.48–0.58) | < 0.001 | 0.50 (0.43–0.56) | < 0.001 |
 2001–2005 | 7753 | 5640 (72.2) | 1295 (16.7) | 818 (10.6) | 0.31 (0.28–0.34) | < 0.001 | 0.28 (0.25–0.31) | < 0.001 |
Sex | ||||||||
 Male | 9998 | 5734 (57.4) | 2270 (22.7) | 1994 (19.9) | Reference |  | Reference |  |
 Female | 8520 | 5799 (68.0) | 1498 (17.6) | 1223 (14.4) | 0.67 (0.62–0.73) | < 0.001 | 0.68 (0.62–0.74) | < 0.001 |
Race | ||||||||
 White | 16,082 | 10,070 (62.6) | 3180 (19.8) | 2832 (17.6) | Reference |  | Reference |  |
 Black | 1694 | 990 (58.4) | 430 (25.4) | 274 (16.2) | 0.90 (0.79–1.03) | 0.139 | 1.13 (0.97–1.31) | 0.117 |
 Others | 742 | 473 (63.7) | 158 (21.3) | 111 (15.0) | 0.82 (0.67–1.01) | 0.064 | 0.91 (0.72–1.14) | 0.396 |
Marital status | ||||||||
 Married | 9789 | 6023 (61.6) | 1921 (19.6) | 1845 (18.8) | Reference |  | Reference |  |
 Unmarried | 8729 | 5630 (64.5) | 1727 (19.8) | 1372 (15.7) | 0.80 (0.74–0.87) | < 0.001 | 1.132 (1.04–1.23) | 0.005 |
Histological type | ||||||||
 NS | 13,562 | 9362 (69.1) | 2284 (16.8) | 1916 (14.1) | Reference |  | Reference |  |
 MC | 3804 | 1658 (43.5) | 1117 (29.4) | 1029 (27.1) | 2.25 (2.07–2.46) | < 0.001 | 1.19 (1.08–1.31) | < 0.001 |
 LR | 729 | 408 (56.0) | 147 (20.1) | 174 (23.9) | 1.91 (1.60–2.28) | < 0.001 | 1.09 (0.89–1.32) | 0.413 |
 LD | 423 | 105 (24.8) | 220 (52.0) | 98 (23.2) | 1.83 (1.46–2.31) | < 0.001 | 0.67 (0.52–0.87) | 0.002 |
Ann Arbor stage | ||||||||
 Early | 11,744 | 8034 (68.4) | 1740 (14.8) | 1970 (16.8) | Reference |  | Reference |  |
 Advanced | 6774 | 3565 (52.6) | 1962 (28.9) | 1247 (18.5) | 1.12 (1.04–1.21) | < 0.001 | 0.92 (0.85–1.02) | 0.393 |
Therapy | ||||||||
 Combined modality | 5410 | 4196 (77.6) | 633 (11.7) | 581 (10.7) | Reference |  | Reference |  |
 RT only | 2985 | 1707 (57.2) | 461 (15.4) | 817 (27.4) | 3.13 (2.78–3.52) | < 0.001 | 1.64 (1.43–1.88) | < 0.001 |
 CT only | 8013 | 4501 (56.1) | 2113 (26.4) | 1399 (17.5) | 1.76 (1.59–1.95) | < 0.001 | 1.08 (0.97–1.22) | 0.175 |
 No/unknown | 2110 | 1129 (53.5) | 561 (26.6) | 420 (19.9) | 2.07 (1.80–2.37) | < 0.001 | 1.09 (0.94–1.27) | 0.241 |