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Fig. 1 | BMC Cancer

Fig. 1

From: Exosomal circEIF3K from cancer-associated fibroblast promotes colorectal cancer (CRC) progression via miR-214/PD-L1 axis

Fig. 1

Hypoxia stimulated exosomal circEIF3K secretion from CAF. A NanoSight quantification of solution or exosome from conditioned media of CAFs under hypoxia treatment. B RT-qPCR showed circEIF3K level in exosome fraction of mock-CM or hypoxia-CM of CAFs. ***p < 0.001. C RT-qPCR showed RNA level of circular RNA (circEIF3K) or mRNA (mEIF3K) treated with or without RNase R. ***p < 0.001. D RT-qPCR showed RNA level of circular RNA (circEIF3K) or mRNA (mEIF3K) in HCT116 cells treated with or without Actinomycin D. ***p < 0.001

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