Fig. 4
From: Interaction between DNMT3B and MYH11 via hypermethylation regulates gastric cancer progression
MYH11 interacts with TNFRSF14 by direct binding in GC cells. A, TNFRSF14 expression in GC cells in response to oe-MYH11 or oe-NC by RT-qPCR; B, TNFRSF14 expression in GC cells in response to oe-MYH11 or oe-NC by western blot; C, the binding sites between MYH11 and TNFRSF14 promoter; D, the enrichment ability of MYH11 on TNFRSF14 promoter examined by ChIP-qPCR; E, the transcriptional activity of TNFRSF14 promoter detected by a luciferase report assay. Each assay was performed at least three times. Statistical significance was analyzed by one-way (panel E) or two-way ANOVA (panels A, B and D) and Tukey’s multiple range tests