Table 1 Demographics of 111 patients with lung adenocarcinoma who underwent surgical resection
variable | All patients (n = 111) | Negative for STAS (n = 75) | Positive for STAS (n = 36) | P value | |
|---|---|---|---|---|---|
Age (years)* | 59.1 ± 9.1 [35–81] | 59.8 ± 9.2 [35–77] | 57.6 ± 8.7 [37–81] | 0.279 | |
Sex | Female | 61 | 39 (52.0%) | 22 (61.1%) | 0.419 |
Male | 50 | 36 (48.0%) | 14 (38.9%) | ||
Smoking status | Never | 71 | 46 (61.3%) | 25 (69.4%) | 0.527 |
Former or current | 40 | 29 (38.7%) | 11 (30.1%) | ||
Location | Upper & middle lobe | 61 | 38 (50.7%) | 23 (63.9%) | 0.225 |
Lower lobe | 50 | 37 (49.3%) | 13 (36.1%) | ||
Surgery | Lobectomy or pneumonectomy | 97 | 61 (81.3%) | 36 (100%) | 0.004 |
Sublobar resection | 14 | 14 (18.7%) | 0 (0.0%) | ||
Tumor Size (mm)* | 22.7 ± 7.9 [8.1–29.5] | 22.3 ± 8.4 [8.1–29.5] | 23.4 ± 6.6 [8.3–29.1] | 0.446 | |
Lymph Node Status | N0 | 89 | 65 (86.7%) | 24 (66.7%) | 0.039 |
N1 | 14 | 7 (9.3%) | 7 (19.4%) | ||
N2 | 8 | 3 (4.0%) | 5 (13.9%) | ||
Histologic Subtypes | Lepidic | 11 | 11 (14.7%) | 0 (0.0%) | 0.001 |
Acinar | 55 | 46 (61.3%) | 9 (25.0%) | ||
Papillary | 6 | 2 (2.6%) | 4 (11.1%) | ||
Micropapillary | 16 | 5 (6.7%) | 11 (30.6%) | ||
Solid | 23 | 11 (14.7%) | 12 (33.3%) | ||
Lymphovascular Invasion | Absent | 91 | 66 (88.0%) | 25 (69.4%) | 0.032 |
Present | 20 | 9 (22.0%) | 11 (30.6%) | ||
Visceral Pleural Invasion | Absent | 101 | 68 (90.7%) | 33 (91.7%) | 0.863 |
Present | 10 | 7 (9.3%) | 3 (8.3%) |