|
variable
| |
All patients (n = 111)
|
Negative for STAS (n = 75)
|
Positive for STAS (n = 36)
|
P value
|
|---|
|
Age (years)*
| |
59.1 ± 9.1 [35–81]
|
59.8 ± 9.2 [35–77]
|
57.6 ± 8.7 [37–81]
|
0.279
|
|
Sex
|
Female
|
61
|
39 (52.0%)
|
22 (61.1%)
|
0.419
|
|
Male
|
50
|
36 (48.0%)
|
14 (38.9%)
|
|
Smoking status
|
Never
|
71
|
46 (61.3%)
|
25 (69.4%)
|
0.527
|
|
Former or current
|
40
|
29 (38.7%)
|
11 (30.1%)
|
|
Location
|
Upper & middle lobe
|
61
|
38 (50.7%)
|
23 (63.9%)
|
0.225
|
|
Lower lobe
|
50
|
37 (49.3%)
|
13 (36.1%)
|
|
Surgery
|
Lobectomy or pneumonectomy
|
97
|
61 (81.3%)
|
36 (100%)
|
0.004
|
|
Sublobar resection
|
14
|
14 (18.7%)
|
0 (0.0%)
|
|
Tumor Size (mm)*
| |
22.7 ± 7.9 [8.1–29.5]
|
22.3 ± 8.4 [8.1–29.5]
|
23.4 ± 6.6 [8.3–29.1]
|
0.446
|
|
Lymph Node Status
|
N0
|
89
|
65 (86.7%)
|
24 (66.7%)
|
0.039
|
|
N1
|
14
|
7 (9.3%)
|
7 (19.4%)
|
|
N2
|
8
|
3 (4.0%)
|
5 (13.9%)
|
|
Histologic Subtypes
|
Lepidic
|
11
|
11 (14.7%)
|
0 (0.0%)
|
0.001
|
|
Acinar
|
55
|
46 (61.3%)
|
9 (25.0%)
|
|
Papillary
|
6
|
2 (2.6%)
|
4 (11.1%)
|
|
Micropapillary
|
16
|
5 (6.7%)
|
11 (30.6%)
|
|
Solid
|
23
|
11 (14.7%)
|
12 (33.3%)
|
|
Lymphovascular Invasion
|
Absent
|
91
|
66 (88.0%)
|
25 (69.4%)
|
0.032
|
|
Present
|
20
|
9 (22.0%)
|
11 (30.6%)
|
|
Visceral Pleural Invasion
|
Absent
|
101
|
68 (90.7%)
|
33 (91.7%)
|
0.863
|
|
Present
|
10
|
7 (9.3%)
|
3 (8.3%)
|
- * Data are mean ± standard deviation. STAS, tumor spread through air spaces
