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Table 3 Association between precancerous conditions and variables investigated

From: Characteristics of gastric precancerous conditions and Helicobacter pylori infection among dyspeptic patients in north-eastern Iran: is endoscopic biopsy and histopathological assessment necessary?

Type of pathology Variation Univariate logistic regression Multivariate logistic regression
OR (95% CI) P-value OR (95% CI) P-value
Precancerous conditions Age ≤ 40 years Reference Reference
Age between 41 and 50 years 10.77 (4.59–25.26) 0.001 10.78 (4.54–25.59) 0.001
Age between 51 and 60 years 11.35 (4.84–26.57) 0.001 9.88 (4.18–23.35) 0.001
Age ≥ 61 years 19.01 (8.24–43.86) 0.001 18.53 (7.94–43.26) 0.001
NSAID consumption 0.34 (0.20–0.58) 0.001 0.34 (0.19–0.60) 0.001
H. pylori infection 4.33 (2.05–9.16) 0.001 4.01 (1.83–8.78) 0.001
Abnormal gastric biopsy Age between 41 and 50 years 2.55 (1.39–4.67) 0.002 2.32 (1.22–4.39) 0.01
Age between 51 and 60 years 2.52 (1.38–4.63) 0.003 2.16 (1.14–4.08) 0.01
Age ≥ 61 years 3.49 (1.79–6.81) 0.001 3.28 (1.63–6.60) 0.001
H. pylori infection 6.29 (3.94–10.01) 0.001 5.92 (3.67–9.55) 0.001
Atrophy Age between 41 and 50 years 12.47 (2.76–56.25) 0.001 11.96 (2.64–52.20) 0.001
Age between 51 and 60 years 23.19 (5.35–100.56) 0.001 20.19 (4.64–87.90) 0.001
Age ≥ 61 years 45.82 (10.80–194.30) 0.001 43.29 (10.16–184.33) 0.001
NSAID consumption 0.37 (0.19–0.73) 0.004 0.40 (0.20–0.82) 0.012
H. pylori infection 3.1 (1.31–7.35) 0.01 2.72 (1.10–6.71) 0.029
Metaplasia Age between 41 and 50 years 7.6 (2.76–20.92) 0.001 7.31 (2.63–20.29) 0.001
Age between 51 and 60 years 10.18 (3.77–27.47) 0.001 8.75 (3.22–23.79) 0.001
Age ≥ 61 years 21.00 (8.01–55.00) 0.001 20.00 (7.57–52.84) 0.001
NSAID consumption 0.35 (0.19–0.66) 0.001 0.37 (0.19–0.71) 0.003
H. pylori infection 3.94 (1.67–9.27) 0.002 3.58 (1.47–8.72) 0.005
Dysplasia Age between 41 and 50 years 15.77 (3.56–69.87) 0.001 16.29 (3.66–72.38) 0.001
Age between 51 and 60 years 8.40 (1.78–39.57) 0.013 7.65 (1.62–36.11) 0.013
Age ≥ 61 years 19.45 (4.44–85.11) 0.001 18.64 (4.25–81.79) 0.001
NSAID consumption 0.33 (0.13–0.80) 0.014 0.33 (0.13–0.82) 0.017
  1. OR odds ratio