Table 3 Association between precancerous conditions and variables investigated

Precancerous conditions

Age ≤ 40 years

Reference

–

Reference

–

Age between 41 and 50 years

10.77 (4.59–25.26)

0.001

10.78 (4.54–25.59)

0.001

Age between 51 and 60 years

11.35 (4.84–26.57)

0.001

9.88 (4.18–23.35)

0.001

Age ≥ 61 years

19.01 (8.24–43.86)

0.001

18.53 (7.94–43.26)

0.001

NSAID consumption

0.34 (0.20–0.58)

0.001

0.34 (0.19–0.60)

0.001

H. pylori infection

4.33 (2.05–9.16)

0.001

4.01 (1.83–8.78)

0.001

Abnormal gastric biopsy

Age between 41 and 50 years

2.55 (1.39–4.67)

0.002

2.32 (1.22–4.39)

0.01

Age between 51 and 60 years

2.52 (1.38–4.63)

0.003

2.16 (1.14–4.08)

0.01

Age ≥ 61 years

3.49 (1.79–6.81)

0.001

3.28 (1.63–6.60)

0.001

H. pylori infection

6.29 (3.94–10.01)

0.001

5.92 (3.67–9.55)

0.001

Atrophy

Age between 41 and 50 years

12.47 (2.76–56.25)

0.001

11.96 (2.64–52.20)

0.001

Age between 51 and 60 years

23.19 (5.35–100.56)

0.001

20.19 (4.64–87.90)

0.001

Age ≥ 61 years

45.82 (10.80–194.30)

0.001

43.29 (10.16–184.33)

0.001

NSAID consumption

0.37 (0.19–0.73)

0.004

0.40 (0.20–0.82)

0.012

H. pylori infection

3.1 (1.31–7.35)

0.01

2.72 (1.10–6.71)

0.029

Metaplasia

Age between 41 and 50 years

7.6 (2.76–20.92)

0.001

7.31 (2.63–20.29)

0.001

Age between 51 and 60 years

10.18 (3.77–27.47)

0.001

8.75 (3.22–23.79)

0.001

Age ≥ 61 years

21.00 (8.01–55.00)

0.001

20.00 (7.57–52.84)

0.001

NSAID consumption

0.35 (0.19–0.66)

0.001

0.37 (0.19–0.71)

0.003

H. pylori infection

3.94 (1.67–9.27)

0.002

3.58 (1.47–8.72)

0.005

Dysplasia

Age between 41 and 50 years

15.77 (3.56–69.87)

0.001

16.29 (3.66–72.38)

0.001

Age between 51 and 60 years

8.40 (1.78–39.57)

0.013

7.65 (1.62–36.11)

0.013

Age ≥ 61 years

19.45 (4.44–85.11)

0.001

18.64 (4.25–81.79)

0.001

NSAID consumption

0.33 (0.13–0.80)

0.014

0.33 (0.13–0.82)

0.017