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Table 4 The enriched hallmark signatures that were significantly associated with NLGN1 by Gene set enrichment analysis (GSEA)

From: Upregulated NLGN1 predicts poor survival in colorectal cancer

 

Gene size

Enrichment score

P value

Hedgehog signaling pathway

53

0.30

<0.001

Glycosaminoglycan biosynthesis heparan sulfate

26

−0.33

<0.001

Pyruvate metabolism

38

−0.38

<0.001

Terpenoid backbone biosynthesis

15

−0.61

<0.001

Biosynthesis of unsaturated fatty acids

19

−0.34

<0.001

RNA degradation

57

− 0.62

<0.001

RNA polymerase

28

−0.62

<0.001

Proteasome

41

−0.69

<0.001

Base excision repair

32

−0.67

<0.001

Mismatch repair

22

−0.72

<0.001

Peroxisome

77

−0.43

<0.001

Protein export

23

−0.57

<0.001

  1. Results from analysis of GSE39582 dataset