Table 1 Patients’ demographics and clinical characteristics (N = 112)*
| Â | Frequency (%) | |
|---|---|---|
Marital status | Single | 15 (13.4%) |
Married | 94 (83.9%) | |
Widowed | 3 (2.7%) | |
Level of education* | Primary | 16 (14.5%) |
Secondary | 61 (55.5%) | |
University | 33 (30%) | |
Profession/Work | No | 78 (69.6%) |
Yes | 34 (30.4%) | |
Socioeconomic status | Low | 8 (8%) |
Middle | 96 (85.7%) | |
High | 7 (6.3%) | |
Alcohol consumption | Yes | 18 (16.1%) |
Smoking | Yes | 26 (23.2%) |
Previous smoker | 4 (3.6%) | |
Hypertension | Yes | 30 (26.8%) |
Diabetes | Yes | 11 (9.8%) |
Dyslipidemia | Yes | 23 (20.5%) |
Presence of metastases | No | 104 (92.9%) |
Yes | 8 (7.1%) | |
Type of metastases | Bone | 6 (75%) |
Lung | 2 (25%) | |
Type of chemotherapy | Adjuvant | 79 (71.2%) |
Neoadjuvant | 24 (21.6%) | |
Palliative | 8 (7.2%) | |
|  | Mean ± Standard Deviation (SD) | Median [25–75 Percentiles] ‡ |
Age (years) | 56.04 ± 11.69 | 56 [49–65] |
Body Mass Index (BMI; Kg/m2) | 25.90 ± 4.62 | 25.65 [23.46–28.14] |
Body Surface Area (BSA; m2) | 1.75 ± 0.16 | 1.74 [1.66–1.86] |
Number of chemotherapy cycles | 4.45 ± 2.35 | 4 [2–6] |
Pain VAS score | 1.68 ± 2.49 | 0 [0–3] |
Psychological factors | ||
 HADS-A | 8.69 ± 5.25 | 9 [4–13] |
  Normal (n; %) | 49 (43.8%) |  |
  Borderline anxiety (n; %) | 22 (19.6%) |  |
  Anxiety (n; %) | 41 (36.6%) |  |
 HADS-D | 7.27 ± 4.59 | 7 [3–11] |
  Normal (n; %) | 60 (53.6%) |  |
  Borderline depression (n; %) | 22 (16.6%) |  |
  Depression (n; %) | 30 (26.8%) |  |
Sleep evaluation | ||
 Insomnia Severity Index (ISI) score | 10.44 ± 7.19 | 9 [5–15.75] |
 Pittsburgh Sleep Quality Index (PSQI) score | 8.91 ± 4.63 | 9 [5–12] |
Cognition~ | ||
 CogPCI score | 56.94 ± 14.29 | 58.5 [49–67] |
 CogPCA score | 22.99 ± 5.55 | 24 [20–26] |
 CogOth score | 13.28 ± 3.17 | 14 [12–16] |
 CogQOL score | 10.02 ± 4.79 | 10 [6–14.75] |
 Total FACT-Cog score | 103.25 ± 23.15 | 107 [95–119] |
Fatigue Score | 42.12 ± 32.10 | 33.33 [11.11–66.67] |