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Table 1 Demographic and clinicopathological characteristics for initial treatment

From: Salvage surgery for patients with residual/persistent diseases after improper or insufficient treatment of oral squamous cell carcinoma: can we rectify these mistakes?

Characteristics Number (%) Overall survival (%) p (Log-rank)
Sex
 Male 68(66.0) 67.6 0.046
 Female 35(34.0) 48.6
Age
  < 60 60(58.3) 60.0 0.744
  ≥ 60 43(41.7) 60.0
Comorbidity
 Cardiovascular diseases 20(19.4) 70.0 0.459
 Diabetes 7(6.8) 57.1
 Others 4(3.9) 100.0
 Combinations 12(11.7) 66.7
 None 60(58.3) 55.0
Site of primary OSCC
 Tongue 36(35.0) 61.1 0.600
 Floor of mouth 13(12.6) 76.9
 Bucca 21(20.4) 70.0
 Lower gingiva 21(20.4) 47.6
 Upper gingiva 8(7.8) 62.5
 Hard palate 4(3.9) 50.0
Primary T stage
 T1 2(2.0) 100.0 0.011
 T2 27(26.2) 74.1
 T3 48(46.6) 64.6
 T4 26(25.2) 38.5
Primary N grade
 N0 64(62.1) 62.5 0.344
 N1 19(18.4) 68.4
 N2 10(9.7) 40.0
 N3 10(9.7) 60.0
Primary stage#
 Early stage 23(22.3) 65.2 (56.2) 0.680
 Late stage 80(77.7) 60.0 (43.4)
DOI of primary OSCC
  > 10 mm 45(43.7) 68.9 0.092
  ≤ 10 mm 58(56.3) 55.2
ENE of primary OSCC
 With ENE 10(9.7) 61.3 0.757
 Without ENE 93(90.3) 60.0
Primary histological grade
 Well differentiated 16(15.5) 68.8 0.747
 Moderately differentiated 65(63.1) 60.0
 Poorly differentiated 22(21.4) 59.1
Neck dissection for primary OSCC
 Bilateral neck dissections 8(7.8) 65.9 0.116
 Ipsilateral neck dissection 51(49.5) 60.8
 None 44(42.7) 37.5
Margin status after primary surgery
 Positive 80(77.7) 60.0 0.711
 Negative 23(22.3) 65.2
Number of positive margins*
 1 54(67.5) 63.0 0.711
 2 25(31.3) 52.0
 3 1(1.3) 100.0
Positive deep margin*
 Yes 37(46.3) 56.8 0.714
 No 43(53.8) 62.8
Primary reconstruction
 Primary closure 18(17.5) 66.7 0.117
 Local flap or skin graft 57(55.3) 66.7
 Free flap and PMMF 28(27.2) 46.4
Neoadjuvant therapy for primary OSCC
 Yes 14(13.6) 35.7 0.006
 No 89(86.4) 65.2
Ceased adjuvant therapy after primary surgery
 No adjuvant therapy 98(95.1) 60.2 0.432
 Ceased adjuvant therapy 5(4.9) 80.0
  1. *: Only patients with positive margins were included
  2. #:The number in the parenthese represented the 5-year salvage rates of the patients with due follow-up