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Table 4 GMDR analysis on the best SNP–SNP and gene- abdominal obesity interaction models

From: RETRACTED ARTICLE: Haplotype analysis on correlation between transcription factor 7-like 2 gene polymorphism and breast cancer risk

Locus no.

Best combination

Cross-validation consistency

Testing balanced accuracy

p-values *

SNP- SNP interactions a

2

rs1225404 rs7903146

8/10

0.524

0.256

3

rs1225404 rs7903146 rs12255372

7/10

0.540

0.324

 4

rs1225404 rs7903146 rs12255372 rs11196205

6/10

0.496

0.624

Gene- abdominal obesity interactions b

 2

rs1225404 abdominal obesity

10/10

0.632

0.010

3

rs1225404 rs7903146 abdominal obesity

9/10

0.518

0.182

 4

rs1225404 rs7903146 rs12255372 abdominal obesity

8/10

0.496

0.532

 5

rs1225404 rs7903146 rs12255372 rs11196205 abdominal obesity

7/10

0.515

0.425

  1. aAdjusted for gender, age, age at menarche, age at menopause, number of children, WC
  2. bAdjusted for gender, age, age at menarche, age at menopause, number of children