Fig. 2

Unsupervised hierarchical clustering analysis of radiomic features. Radiomic features with predictive ability in the univariate analysis are labeled. Radiomic features included in the final TMB-predicting model are marked in red. Based on the homogeneity and heterogeneity of the radiomic features, all cases were divided into two clustering groups by the unsupervised hierarchical clustering analysis. Clinical and genomic outcomes were compared between the two groups. TMB: Tumor mutation burden; BMI: body mass index