Table 4 Mean absorbed dose per amount of injected activity (Gy/MBq) for CLB-BAR (present study), CLB-GE (present study), IMR-32 (present study), GOT1, GOT2 and NCI-H69. Data were corrected for decay before estimation of the absorbed dose
From: Neuroblastoma xenograft models demonstrate the therapeutic potential of 177Lu-octreotate
Cell line | CLB-BAR (present study) | CLB-GE (present study) | IMR-32 (present study) | GOT1 [35] | GOT2 [36] | NCI-H69 [37] | |||
|---|---|---|---|---|---|---|---|---|---|
Activity injected | 0.15 MBq | 1.5 MBq | 15 MBq | 0.15 MBq | 15 MBq | 15 MBq | 15 MBq | 10 MBq | 3.3 MBq |
 Adrenals | 1.4 | 0.30 | 0.096 | 1.9 | 0.24 | 0.15 | 0.079 | 0.051 | – |
 Blood | 0.063 | 0.029 | 0.0061 | 0.14 | 0.042 | 0.014 | 0.00069 | 0.00056 | – |
 Brain | 0.090 | 0.0091 | 0.0065 | 0.018 | 0.011 | 0.0065 | – | – | – |
 Kidneys | 2.1 | 2.7 | 1.3 | 2.1 | 1.1 | 1.4 | 0.32 | 0.32 | – |
 Liver | 0.18 | 0.067 | 0.029 | 0.31 | 0.052 | 0.085 | 0.011 | 0.0091 | – |
 Lungs | 1.8 | 0.46 | 0.10 | 4.6 | 0.26 | 0.16 | 0.038 | – | – |
 Spleen | 0.22 | 0.16 | 0.049 | 0.54 | 0.057 | 0.061 | 0.012 | 0.0079 | – |
 Tumor | 3.6 | 2.9 | 0.45 | 2.4 | 3.6 | 1.9 | 0.27 | 0.013 | 0.29 |