|
Variables
|
Univariable analysis
|
Multivariable analysis
|
|---|
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
P value
|
|---|
|
Treatment regimen
|
|
mFOLFIRINOX vs Gemox
|
0.595 (0.312–1.135)
|
0.099
|
0.547 (0.264–1.131)
|
0.103
|
|
Age
|
|
>58 vs ≤58
|
1.089 (0.567–2.092)
|
0.798
| | |
|
Sex
|
|
male vs female
|
0.896 (0.650–1.235)
|
0.504
| | |
|
ECOG
|
|
1 vs 0
|
1.709 (0.883–3.310)
|
0.112
|
2.148 (1.028–4.488)
|
0.042
|
|
Primary tumor sites
|
|
Intrahepatic
|
Ref
| | | |
|
Hilar
|
1.609 (0.827–3.129)
|
0.161
|
2.123 (1.023–4.402)
|
0.043
|
|
Distal
|
0.893 (0.207–3.846)
|
0.879
|
0.890 (0.199–3.983)
|
0.878
|
|
Disease status
|
|
Metastasis vs Locally advanced
|
0.939 (0.660–1.335)
|
0.724
| | |
|
Liver metastasis
|
1.393 (0.716–2.710)
|
0.329
| | |
|
CA19–9
|
|
>40 vs ≤40
|
3.198 (1.237–8.266)
|
0.016
|
4.972 (1.768–13.980)
|
0.002
|
- Bold values are statistically significant (p ≤ 0.05)
- Ref reference, HR hazard ratio, CI confidence interval, ECOG Eastern Cooperative Oncology Group
