Fig. 1

LINC01287 is up-regulated in colon cancer tissues and closely associated with poor prognosis. A, heat map showed the top 50 dyregulated lncRNAs in 4 colon cancer tissues and paired normal samples identified by transcriptome sequencing. B, relative LINC01287 expression in 60 colon cancer tissues and paired normal samples was tested by qRT-PCR. Compared with paired normal samples using two-tailed Student’s t-test, **p ≤ 0.001. C, relative level of LINC01287 in colon cancer patients according to tumor stage. Compared with tumor stage I using two-tailed Student’s t-test, *p ≤ 0.05, **p ≤ 0.001. D, overall survival of colon cancer patients with high or low LINC01287 expression was plotted by Kaplan-Meier survival method. E, expression of LINC01287 in colon cancer cells was tested by qRT-PCR