|
biological processes
|
GO:0007588 ~ excretion
|
7
|
2.64E-07
|
NPHS2, CLCNKB, UMOD, ATP6V1B1, ATP6V0A4, KCNJ1, AQP2
|
|
GO:0001666 ~ response to hypoxia
|
11
|
5.42E-07
|
CAV1, NOL3, CA9, PLOD2, CXCR4, EGLN3, TLR2, HSD11B2, ABAT, CASP1, ANGPTL4
|
|
GO:0090383 ~ phagosome acidification
|
4
|
9.87E-04
|
ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2
|
|
GO:0033572 ~ transferrin transport
|
4
|
0.002115
|
ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2
|
|
GO:0008286 ~ insulin receptor signaling pathway
|
5
|
0.002575
|
CAV2, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2
|
|
GO:0032755 ~ positive regulation of interleukin-6 production
|
4
|
0.004349
|
P2RX7, TLR2, FCER1G, TLR3
|
|
GO:0034220 ~ ion transmembrane transport
|
7
|
0.004506
|
FXYD4, CLCNKB, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2, AQP2
|
|
GO:0015695 ~ organic cation transport
|
3
|
0.00525
|
RHCG, SLC7A8, RHBG
|
|
GO:0006885 ~ regulation of pH
|
3
|
0.005972
|
RHCG, ATP6V1B1, ATP6V0A4
|
|
GO:0090090 ~ negative regulation of canonical Wnt signaling pathway
|
6
|
0.006989
|
CTHRC1, CAV1, SOST, GPC3, SFRP1, PSMB9
|
|
GO:0042493 ~ response to drug
|
8
|
0.007086
|
P2RX7, CA9, SFRP1, LGALS1, SLC34A1, HSD11B2, ABAT, NNMT
|
|
GO:0008152 ~ metabolic process
|
6
|
0.007913
|
ENPP6, LPCAT1, SUCLG1, MAN1C1, ACSF2, ACAA1
|
|
GO:0032092 ~ positive regulation of protein binding
|
4
|
0.010136
|
CTHRC1, CAV1, PLK2, TRIB3
|
|
GO:0055074 ~ calcium ion homeostasis
|
3
|
0.011171
|
CAV1, ATP6V1B1, CALB1
|
|
GO:0006508 ~ proteolysis
|
10
|
0.011293
|
C1QA, C1QB, GGT6, SFRP1, C3, CTSS, CASP1, PLG, DPEP1, XPNPEP2
|
|
GO:0055114 ~ oxidation-reduction process
|
11
|
0.011711
|
ALDH6A1, TYRP1, PLOD2, NDUFA4L2, RRM2, EGLN3, HSD11B2, ALDH4A1, DIO1, DCXR, HPD
|
|
GO:0010951 ~ negative regulation of endopeptidase activity
|
5
|
0.012067
|
KNG1, C3, SERPINA5, HRG, CSTA
|
|
GO:0050900 ~ leukocyte migration
|
5
|
0.012407
|
SLC16A3, CAV1, SLC7A8, FCER1G, ITGB2
|
|
GO:0045880 ~ positive regulation of smoothened signaling pathway
|
3
|
0.013221
|
GPC3, SFRP1, FGF9
|
|
GO:0001798 ~ positive regulation of type IIa hypersensitivity
|
2
|
0.014597
|
C3, FCER1G
|
|
GO:2000054 ~ negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
|
2
|
0.014597
|
SOST, SFRP1
|
|
GO:0061621 ~ canonical glycolysis
|
3
|
0.01542
|
ENO2, PFKP, HK2
|
|
GO:0001503 ~ ossification
|
4
|
0.020939
|
SOST, SLC34A1, ATP6V1B1, ATP6V0A4
|
|
GO:0006954 ~ inflammatory response
|
8
|
0.021562
|
KNG1, TNFAIP6, P2RX7, CXCR4, C3, TLR2, TLR3, ITGB2
|
|
GO:0050717 ~ positive regulation of interleukin-1 alpha secretion
|
2
|
0.021815
|
P2RX7, CASP1
|
|
GO:2000116 ~ regulation of cysteine-type endopeptidase activity
|
2
|
0.021815
|
BIRC3, PSMB9
|
|
GO:0070634 ~ transepithelial ammonium transport
|
2
|
0.021815
|
RHCG, RHBG
|
|
GO:0019065 ~ receptor-mediated endocytosis of virus by host cell
|
2
|
0.021815
|
CAV2, CAV1
|
|
GO:0015991 ~ ATP hydrolysis coupled proton transport
|
3
|
0.022874
|
ATP6V1B1, ATP6V0A4, ATP6V0D2
|
|
GO:0051480 ~ regulation of cytosolic calcium ion concentration
|
3
|
0.022874
|
CAV1, PVALB, CALB1
|
|
GO:0001525 ~ angiogenesis
|
6
|
0.024169
|
CAV1, FGF9, TGFBI, HRG, FGF1, ANGPTL4
|
|
GO:0002931 ~ response to ischemia
|
3
|
0.024234
|
CAV1, NOL3, HK2
|
|
GO:0072221 ~ metanephric distal convoluted tubule development
|
2
|
0.028982
|
UMOD, CALB1
|
|
GO:0002283 ~ neutrophil activation involved in immune response
|
2
|
0.028982
|
FCER1G, TYROBP
|
|
GO:0007162 ~ negative regulation of cell adhesion
|
3
|
0.029996
|
KNG1, TGFBI, HRG
|
|
GO:0006955 ~ immune response
|
8
|
0.03533
|
RGS1, TNFSF13B, C3, ENPP3, TLR2, CTSS, FCGR3A, FCGR3B
|
|
GO:0070836 ~ caveola assembly
|
2
|
0.036096
|
CAV2, CAV1
|
|
GO:0015696 ~ ammonium transport
|
2
|
0.036096
|
RHCG, RHBG
|
|
GO:0006873 ~ cellular ion homeostasis
|
2
|
0.036096
|
RHCG, SLC4A1
|
|
GO:0019740 ~ nitrogen utilization
|
2
|
0.036096
|
RHCG, RHBG
|
|
GO:0010543 ~ regulation of platelet activation
|
2
|
0.036096
|
FCER1G, HRG
|
|
GO:0051005 ~ negative regulation of lipoprotein lipase activity
|
2
|
0.036096
|
APOC1, ANGPTL4
|
|
GO:0034123 ~ positive regulation of toll-like receptor signaling pathway
|
2
|
0.036096
|
TLR2, TLR3
|
|
GO:0031623 ~ receptor internalization
|
3
|
0.039536
|
CAV1, FCER1G, ITGB2
|
|
GO:0006094 ~ gluconeogenesis
|
3
|
0.041225
|
ENO2, FBP1, PCK2
|
|
GO:0050776 ~ regulation of immune response
|
5
|
0.041952
|
C3, ITGB2, FCGR3A, TREM2, TYROBP
|
|
GO:0030514 ~ negative regulation of BMP signaling pathway
|
3
|
0.04294
|
CAV1, SOST, SFRP1
|
|
GO:0000187 ~ activation of MAPK activity
|
4
|
0.043944
|
P2RX7, CXCR4, FGF1, DUSP9
|
|
GO:0007596 ~ blood coagulation
|
5
|
0.046407
|
P2RX7, SERPINA5, FCER1G, ENTPD1, PLG
|
|
GO:0032760 ~ positive regulation of tumor necrosis factor production
|
3
|
0.046448
|
TLR2, FCER1G, TLR3
|
|
cell composition
|
GO:0070062 ~ extracellular exosome
|
61
|
4.70E-17
|
FGF9, SLC7A8, CALB1, AQP2, EFHD1, GPC3, PVALB, CXCR4, PLOD2, SERPINA5, TMEM52B, TGFBI, SLC4A1, FCGR3A, ATP6V0D2, FCGR3B, DPEP1, HPD, KNG1, ALDH6A1, CRYAA, SUCLG1, SLC22A8, PFKP, FBP1, C1QA, C1QB, RHCG, MNDA, ABAT, CSTA, CHL1, SH3GL2, ENPP6, C3, ENPP3, APOC1, ITGB2, UMOD, ATP6V1B1, ENO2, HS6ST2, HRG, SUCNR1, ENTPD1, SLC12A3, LGALS1, PCK2, MAN1C1, PLG, PSMB9, XPNPEP2, AFM, GGT6, SFRP1, NPHS2, SLC13A3, FABP1, ATP6V0A4, IGFBP3, DCXR
|
|
GO:0016323 ~ basolateral plasma membrane
|
12
|
6.23E-08
|
CLDN8, CAV1, RHCG, CA9, SLC22A7, SLC22A8, SLC7A8, RHBG, UMOD, SLC4A1, ATP6V1B1, AQP2
|
|
GO:0005886 ~ plasma membrane
|
53
|
4.79E-06
|
CLDN8, TLR2, SLC7A8, AQP2, GPC3, CXCR4, TGFBI, SLC4A1, FCGR3A, FCGR3B, DPEP1, KNG1, COL23A1, SLC22A7, SUCLG1, SLC22A8, SLC34A1, TNFSF13B, RHCG, CA9, ATP6V1G3, TREM2, SH3GL2, CHL1, ENPP6, CAV2, CAV1, FXYD4, C3, RHBG, TRIB3, CLCNKB, ITGB2, KCNJ1, ENO2, TMEM30B, FCER1G, HRG, SUCNR1, ENTPD1, TYROBP, SLC12A3, PLG, XPNPEP2, SLC16A3, P2RX7, RGS1, SFRP1, NPHS2, SLC13A3, DIO1, ATP6V0A4, DCXR
|
|
GO:0005887 ~ integral component of plasma membrane
|
25
|
5.00E-05
|
CAV2, CAV1, FXYD4, SLC12A3, SLC22A7, ENPP3, SLC22A8, TLR2, RHBG, SLC34A1, SLC7A8, TLR3, CLCNKB, AQP2, SLC16A3, P2RX7, LAPTM5, GPC3, RHCG, NPHS2, FCER1G, SLC13A3, SLC4A1, ENTPD1, TYROBP
|
|
GO:0016471 ~ vacuolar proton-transporting V-type ATPase complex
|
4
|
7.28E-05
|
ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2
|
|
GO:0072562 ~ blood microparticle
|
8
|
1.04E-04
|
KNG1, C1QB, AFM, C3, HRG, SLC4A1, PLG, ANGPTL4
|
|
GO:0005578 ~ proteinaceous extracellular matrix
|
10
|
1.24E-04
|
CTHRC1, SOST, GPC3, SFRP1, LGALS1, TGFBI, UMOD, FGF1, CHL1, ANGPTL4
|
|
GO:0016324 ~ apical plasma membrane
|
10
|
2.30E-04
|
CAV1, RHCG, SLC12A3, SLC34A1, UMOD, ATP6V1B1, ATP6V0A4, ATP6V0D2, DPEP1, AQP2
|
|
GO:0005615 ~ extracellular space
|
22
|
4.94E-04
|
KNG1, CTHRC1, C3, FGF9, LGALS1, HILPDA, CTSS, PLG, TNFAIP6, AFM, GPC3, SOST, TNFSF13B, SFRP1, SERPINA5, TGFBI, ENO2, CSTA, FGF1, IGFBP3, DPEP1, ANGPTL4
|
|
GO:0031225 ~ anchored component of membrane
|
6
|
0.001254
|
ENPP6, GPC3, UMOD, FCGR3B, DPEP1, XPNPEP2
|
|
GO:0016021 ~ integral component of membrane
|
53
|
0.002201
|
CLDN8, TLR2, SLC7A8, TLR3, AQP2, CXCR4, EVI2A, TMEM52B, SMIM5, SLC4A1, FCGR3A, FCGR3B, COL23A1, SLC22A7, SLC22A8, SLC34A1, DMRT2, HEPACAM2, TNFSF13B, CA9, RHCG, SPAG4, HSD11B2, TREM2, CHL1, NETO2, CAV2, TYRP1, CAV1, TMEM213, ENPP3, RHBG, CLCNKB, UMOD, KCNJ1, SEMA5B, LPCAT1, TMEM30B, FCER1G, HS6ST2, SUCNR1, ENTPD1, MS4A6A, TYROBP, TMEM45A, SLC12A3, NDUFA4L2, HILPDA, GGT6, SFRP1, SLC13A3, DIO1, ATP6V0A4
|
|
GO:0043234 ~ protein complex
|
10
|
0.002667
|
CAV2, CAV1, SOST, PVALB, SERPINA5, NPHS2, DDB2, FABP1, PRKCDBP, BIRC3
|
|
GO:0005576 ~ extracellular region
|
22
|
0.004463
|
KNG1, ENPP6, FGF9, C3, APOC1, UMOD, CTSS, PLG, C1QA, C1QB, AFM, SOST, TNFSF13B, SFRP1, SERPINA5, TGFBI, HRG, FGF1, TREM2, CASP1, IGFBP3, ANGPTL4
|
|
GO:0009986 ~ cell surface
|
11
|
0.005205
|
SFRP1, CXCR4, LGALS1, TLR2, SLC34A1, FCER1G, TLR3, HILPDA, ITGB2, PLG, TYROBP
|
|
GO:0002080 ~ acrosomal membrane
|
3
|
0.007858
|
CAV2, CAV1, SERPINA5
|
|
GO:0005602 ~ complement component C1 complex
|
2
|
0.014107
|
C1QA, C1QB
|
|
GO:0045121 ~ membrane raft
|
6
|
0.015662
|
CAV2, CAV1, NPHS2, TLR2, SLC34A1, BIRC3
|
|
GO:0000139 ~ Golgi membrane
|
10
|
0.024687
|
CAV2, CAV1, LPCAT1, ST8SIA4, TLR3, HS6ST2, HEPACAM2, MAN1C1, SH3GL2, HPD
|
|
GO:0005581 ~ collagen trimer
|
4
|
0.027574
|
C1QA, CTHRC1, C1QB, COL23A1
|
|
GO:0005759 ~ mitochondrial matrix
|
7
|
0.028942
|
PDK1, ALDH6A1, SUCLG1, ALDH4A1, ABAT, PCK2, ACSF2
|
|
GO:0005782 ~ peroxisomal matrix
|
3
|
0.042028
|
ACOX2, FABP1, ACAA1
|
|
molecular function
|
GO:0019864 ~ IgG binding
|
4
|
6.11E-05
|
FCER1G, UMOD, FCGR3A, FCGR3B
|
|
GO:0008201 ~ heparin binding
|
7
|
0.001175
|
KNG1, SOST, SFRP1, FGF9, SERPINA5, HRG, FGF1
|
|
GO:0005102 ~ receptor binding
|
10
|
0.001189
|
KNG1, ACOX2, P2RX7, CAV1, TNFSF13B, C3, HRG, HILPDA, PLG, TYROBP
|
|
GO:0030506 ~ ankyrin binding
|
3
|
0.009327
|
RHCG, RHBG, SLC4A1
|
|
GO:0001530 ~ lipopolysaccharide binding
|
3
|
0.011232
|
P2RX7, TLR2, TREM2
|
|
GO:0043027 ~ cysteine-type endopeptidase inhibitor activity involved in apoptotic process
|
3
|
0.012243
|
NOL3, BIRC3, DPEP1
|
|
GO:0015301 ~ anion:anion antiporter activity
|
3
|
0.012243
|
SLC22A7, SLC22A8, SLC4A1
|
|
GO:0051117 ~ ATPase binding
|
4
|
0.017177
|
CAV1, FXYD4, ATP6V1G3, ATP6V0A4
|
|
GO:0042802 ~ identical protein binding
|
12
|
0.022021
|
CLDN8, CAV1, NOL3, SFRP1, CRYAA, FBP1, ALDH4A1, TLR3, SH3GL2, DCXR, TYROBP, ANGPTL4
|
|
GO:0015078 ~ hydrogen ion transmembrane transporter activity
|
3
|
0.022995
|
ATP6V1B1, ATP6V0A4, ATP6V0D2
|
|
GO:0004869 ~ cysteine-type endopeptidase inhibitor activity
|
3
|
0.025762
|
KNG1, HRG, CSTA
|
