Treatment optimization of pelvic external beam radiation and/or vaginal brachytherapy for patients with stage I to II high-risk Endometrioid adenocarcinoma: a retrospective multi-institutional analysis

Table 1 Baseline clinical characteristics for patients treated with adjuvant EBRT with/or VBT

	Patients (N = 218)
	EBRT(n = 51)		VBT(n = 25)		EBRT + VBT (n = 142)		p-value
Clinical Characteristic	No.	%	No.	%	No.	%
Age, years							0.002
Mean	53.31		60.96		54.36
Range	23–84		42–85		34–75
Lymphadenectomy							0.867
No	7	13.7	4	16.0	17	12.0
Yes	44	86.3	21	84.0	125	88.0
Mean	18.69		21.40		18.73		0.054
Range	0–50		0–45		0–65
Stage (FIGO 2009)							0.000
IB	14	27.5	20	80.0	44	31.0
II	37	72.5	5	20.0	98	69.0
Grade							0.003
1	4	7.8	3	12.0	32	25.5
2	20	39.2	2	8.0	47	33.1
3	27	52.9	20	80.0	63	44.4
Myometrial invasion							0.294
< 1/2	13	25.5	4	16.0	43	30.3
≥ 1/2	35	68.6	21	84.0	95	66.9
Missing	3	5.9			4	2.8
Invasion of lower uterine segment							0.205
N0	28	54.9	19	76.0	86	60.6
Yes	23	45.1	6	24.0	56	39.4
LVSI							0.224
No	40	78.4	16	64.0	113	79.6
Yes	11	21.6	9	36.0	29	20.4
Chemotherapy							0.105
No	26	51.0	19	76.0	76	53.5
Yes	25	49.0	6	24.0	60	42.3
Missing					6	4.2

Abbreviation: FIGO International Federation of Gynecology and Obstetrics, EBRT External Beam Radiation, VBT Vaginal Brachytherapy, LVSI Lymphovascular Space Invasion

ISSN: 1471-2407