Table 1 Demographic and treatment variables during chemoradiation
|
Taking protease inhibitors n (%) |
Not taking protease inhibitors n (%) | p-value | |
|---|---|---|---|
| 153 (69.86) | 66 (30.14) | ||
| Age at diagnosis | 0.19 | ||
| < 40 | 10 (6.54) | 2 (3.03) | |
| 40–59 | 104 (67.97) | 40 (60.61) | |
| 60+ | 39 (25.49) | 24 (36.36) | |
| Race/Ethnicity | 0.78 | ||
| African American | 55 (35.95) | 21 (31.82) | |
| Caucasian | 78 (50.98) | 33 (50.00) | |
| Hispanic | 11 (7.19) | 7 (10.61) | |
| Other/Unknown | 9 (5.88) | 5 (7.58) | |
| Year HIV Diagnosed | 0.37 | ||
| < 2000 | 103 (67.32) | 39 (59.09) | |
| 2000–2009 | 39 (25.49) | 23 (34.85) | |
| 2010–2016 | 11 (7.19) | 4 (6.06) | |
| Smoker | 0.80 | ||
| Current | 76 (49.67) | 37 (56.06) | |
| Former | 28 (18.30) | 10 (15.15) | |
| Never | 41 (26.80) | 15 (22.73) | |
| Unknown | 8 (5.23) | 4 (6.06) | |
| Stage | 0.28 | ||
| I | 21 (13.73) | 15 (22.73) | |
| II | 73 (47.71) | 34 (51.52) | |
| IIIA | 15 (9.80) | 3 (4.55) | |
| IIIB | 35 (22.88) | 13 (19.70) | |
| IV | 6 (3.92) | 1 (1.52) | |
| Unknown | 3 (1.96) | 0 (0) | |
| CD4 at HIV Diagnosis | < 0.01 | ||
| ≤ 200 | 55 (35.95) | 20 (30.30) | |
| > 200 | 59 (38.56) | 42 (63.64) | |
| Unknown | 39 (25.49) | 4 (6.06) | |
| CD4 at Cancer Diagnosis | < 0.01 | ||
| ≤ 200 | 43 (28.10) | 8 (12.12) | |
| > 200 | 101 (66.01) | 58 (87.88) | |
| Unknown | 9 (5.88) | 0 (0) | |
| Nadir CD4 during Radiation | < 0.01 | ||
| ≤ 200 | 79 (51.63) | 20 (30.30) | |
| > 200 | 33 (21.57) | 25 (37.88) | |
| missing | 41 (26.80) | 21 (31.82) | |
| BMI | 0.05 | ||
| < 25 | 76 (49.67) | 37 (56.06) | |
| 25–29.9 | 53 (34.64) | 18 (27.27) | |
| ≥ 30 | 14 (9.15) | 11 (16.67) | |
| Unknown | 10 (6.54) | 0 (0) | |
| Alcohol Use | 0.73 | ||
| Yes | 57 (37.25) | 23 (34.85) | |
| No | 96 (62.75) | 43 (65.15) | |
| History of prior cancer | 0.14 | ||
| Yes | 22 (14.38) | 14 (21.21) | |
| No | 129 (84.31) | 49 (74.24) | |
| Unknown | 2 (1.31) | 3 (4.55) | |
| Radiation Modality | 0.87 | ||
| 2D + 3D | 54 (35.29) | 21 (31.82) | |
| IMRT | 52 (33.99) | 23 (34.85) | |
| Unknown | 47 (30.72) | 22 (33.33) | |
| Completed Radiation Treatment | 0.48 | ||
| Yes | 134 (87.58) | 60 (90.91) | |
| No | 19 (12.42) | 6 (9.09) | |
| Length of Radiation Treatment | 0.59 | ||
| ≤ 50 days | 86 (56.21) | 42 (63.64) | |
| > 50 days | 61 (39.87) | 22 (33.33) | |
| Unknown | 6 (3.92) | 2 (3.03) | |
| Chemotherapy Regimen | 0.05 | ||
| 5FU + mitomycin C | 115 (75.16) | 47 (71.21) | |
| 5FU + cisplatin | 20 (13.07) | 4 (6.06) | |
| other | 18 (11.76) | 15 (22.73) | |
| Chemotherapy Dose Reduction | 0.25 | ||
| Yes | 49 (32.03) | 16 (24.24) | |
| No | 104 (67.97) | 50 (75.76) |