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Table 1 Demographic and treatment variables during chemoradiation

From: The association between protease inhibitors and anal cancer outcomes in veterans living with HIV treated with definitive chemoradiation: a retrospective study

 

Taking protease inhibitors

n (%)

Not taking protease inhibitors

n (%)

p-value

153 (69.86)

66 (30.14)

 

Age at diagnosis

  

0.19

  < 40

10 (6.54)

2 (3.03)

 

 40–59

104 (67.97)

40 (60.61)

 

 60+

39 (25.49)

24 (36.36)

 

Race/Ethnicity

  

0.78

 African American

55 (35.95)

21 (31.82)

 

 Caucasian

78 (50.98)

33 (50.00)

 

 Hispanic

11 (7.19)

7 (10.61)

 

 Other/Unknown

9 (5.88)

5 (7.58)

 

Year HIV Diagnosed

  

0.37

  < 2000

103 (67.32)

39 (59.09)

 

 2000–2009

39 (25.49)

23 (34.85)

 

 2010–2016

11 (7.19)

4 (6.06)

 

Smoker

  

0.80

 Current

76 (49.67)

37 (56.06)

 

 Former

28 (18.30)

10 (15.15)

 

 Never

41 (26.80)

15 (22.73)

 

 Unknown

8 (5.23)

4 (6.06)

 

Stage

  

0.28

 I

21 (13.73)

15 (22.73)

 

 II

73 (47.71)

34 (51.52)

 

 IIIA

15 (9.80)

3 (4.55)

 

 IIIB

35 (22.88)

13 (19.70)

 

 IV

6 (3.92)

1 (1.52)

 

 Unknown

3 (1.96)

0 (0)

 

CD4 at HIV Diagnosis

  

< 0.01

  ≤ 200

55 (35.95)

20 (30.30)

 

  > 200

59 (38.56)

42 (63.64)

 

 Unknown

39 (25.49)

4 (6.06)

 

CD4 at Cancer Diagnosis

  

< 0.01

  ≤ 200

43 (28.10)

8 (12.12)

 

  > 200

101 (66.01)

58 (87.88)

 

 Unknown

9 (5.88)

0 (0)

 

Nadir CD4 during Radiation

  

< 0.01

  ≤ 200

79 (51.63)

20 (30.30)

 

  > 200

33 (21.57)

25 (37.88)

 

 missing

41 (26.80)

21 (31.82)

 

BMI

  

0.05

  < 25

76 (49.67)

37 (56.06)

 

 25–29.9

53 (34.64)

18 (27.27)

 

 ≥ 30

14 (9.15)

11 (16.67)

 

 Unknown

10 (6.54)

0 (0)

 

Alcohol Use

  

0.73

 Yes

57 (37.25)

23 (34.85)

 

 No

96 (62.75)

43 (65.15)

 

History of prior cancer

  

0.14

 Yes

22 (14.38)

14 (21.21)

 

 No

129 (84.31)

49 (74.24)

 

 Unknown

2 (1.31)

3 (4.55)

 

Radiation Modality

  

0.87

 2D + 3D

54 (35.29)

21 (31.82)

 

 IMRT

52 (33.99)

23 (34.85)

 

 Unknown

47 (30.72)

22 (33.33)

 

Completed Radiation Treatment

  

0.48

 Yes

134 (87.58)

60 (90.91)

 

 No

19 (12.42)

6 (9.09)

 

Length of Radiation Treatment

  

0.59

  ≤ 50 days

86 (56.21)

42 (63.64)

 

  > 50 days

61 (39.87)

22 (33.33)

 

 Unknown

6 (3.92)

2 (3.03)

 

Chemotherapy Regimen

  

0.05

 5FU + mitomycin C

115 (75.16)

47 (71.21)

 

 5FU + cisplatin

20 (13.07)

4 (6.06)

 

 other

18 (11.76)

15 (22.73)

 

Chemotherapy Dose Reduction

  

0.25

 Yes

49 (32.03)

16 (24.24)

 

 No

104 (67.97)

50 (75.76)

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