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Table 1 Demographic and treatment variables during chemoradiation

From: The association between protease inhibitors and anal cancer outcomes in veterans living with HIV treated with definitive chemoradiation: a retrospective study

  Taking protease inhibitors
n (%)
Not taking protease inhibitors
n (%)
p-value
153 (69.86) 66 (30.14)  
Age at diagnosis    0.19
  < 40 10 (6.54) 2 (3.03)  
 40–59 104 (67.97) 40 (60.61)  
 60+ 39 (25.49) 24 (36.36)  
Race/Ethnicity    0.78
 African American 55 (35.95) 21 (31.82)  
 Caucasian 78 (50.98) 33 (50.00)  
 Hispanic 11 (7.19) 7 (10.61)  
 Other/Unknown 9 (5.88) 5 (7.58)  
Year HIV Diagnosed    0.37
  < 2000 103 (67.32) 39 (59.09)  
 2000–2009 39 (25.49) 23 (34.85)  
 2010–2016 11 (7.19) 4 (6.06)  
Smoker    0.80
 Current 76 (49.67) 37 (56.06)  
 Former 28 (18.30) 10 (15.15)  
 Never 41 (26.80) 15 (22.73)  
 Unknown 8 (5.23) 4 (6.06)  
Stage    0.28
 I 21 (13.73) 15 (22.73)  
 II 73 (47.71) 34 (51.52)  
 IIIA 15 (9.80) 3 (4.55)  
 IIIB 35 (22.88) 13 (19.70)  
 IV 6 (3.92) 1 (1.52)  
 Unknown 3 (1.96) 0 (0)  
CD4 at HIV Diagnosis    < 0.01
  ≤ 200 55 (35.95) 20 (30.30)  
  > 200 59 (38.56) 42 (63.64)  
 Unknown 39 (25.49) 4 (6.06)  
CD4 at Cancer Diagnosis    < 0.01
  ≤ 200 43 (28.10) 8 (12.12)  
  > 200 101 (66.01) 58 (87.88)  
 Unknown 9 (5.88) 0 (0)  
Nadir CD4 during Radiation    < 0.01
  ≤ 200 79 (51.63) 20 (30.30)  
  > 200 33 (21.57) 25 (37.88)  
 missing 41 (26.80) 21 (31.82)  
BMI    0.05
  < 25 76 (49.67) 37 (56.06)  
 25–29.9 53 (34.64) 18 (27.27)  
 ≥ 30 14 (9.15) 11 (16.67)  
 Unknown 10 (6.54) 0 (0)  
Alcohol Use    0.73
 Yes 57 (37.25) 23 (34.85)  
 No 96 (62.75) 43 (65.15)  
History of prior cancer    0.14
 Yes 22 (14.38) 14 (21.21)  
 No 129 (84.31) 49 (74.24)  
 Unknown 2 (1.31) 3 (4.55)  
Radiation Modality    0.87
 2D + 3D 54 (35.29) 21 (31.82)  
 IMRT 52 (33.99) 23 (34.85)  
 Unknown 47 (30.72) 22 (33.33)  
Completed Radiation Treatment    0.48
 Yes 134 (87.58) 60 (90.91)  
 No 19 (12.42) 6 (9.09)  
Length of Radiation Treatment    0.59
  ≤ 50 days 86 (56.21) 42 (63.64)  
  > 50 days 61 (39.87) 22 (33.33)  
 Unknown 6 (3.92) 2 (3.03)  
Chemotherapy Regimen    0.05
 5FU + mitomycin C 115 (75.16) 47 (71.21)  
 5FU + cisplatin 20 (13.07) 4 (6.06)  
 other 18 (11.76) 15 (22.73)  
Chemotherapy Dose Reduction    0.25
 Yes 49 (32.03) 16 (24.24)  
 No 104 (67.97) 50 (75.76)