Functions and clinical significance of KLRG1 in the development of lung adenocarcinoma and immunotherapy

BMC Cancer

Table 4 The association between KLRG1, BTK, CCR2, SCML4 expression and the demographic and clinicopathological parameters

Outcome ^a	KLRG1 expression			BTK expression			CCR2 expression			SCML4 expression
Outcome ^a	Low	High	P value	Low	High	P value	Low	High	P value	Low	High	P value
Age / year			0.250			0.082			0.040			0.172
<65	145	73		132	86		134	84		96	122
≥ 65	160	111		142	129		136	135		97	174
Gender			0.710			0.156			0.029			0.006
Male	146	84		137	93		140	90		105	125
Female	165	104		141	128		134	135		92	177
Mutations / number			0.615			0.067			0692			0.103
≤ 230	92	50		90	54		77	67		56	88
>230	52	25		40	35		39	36		37	38
Smoking history / Category^b			0.628			0.112			0.280			0.937
1	40	31		32	39		32	39		26	45
2, 3, 4, 5	262	152		239	175		235	179		165	249
Neoplasm Disease Stage			0.001			0.022			0.004			0.014
I, II	224	162		202	184		196	190		141	245
III, IV, V	82	23		72	33		72	33		54	51

P values are derived from one-way analysis of variance
^a A total of 499 samples were analyzed. Age: N = 489, NA = 10; Stage: N = 491, NA = 8; Mutations: N = 219, NA = 280; Smoking History: N = 485, NA = 14. N: Number; NA: Not Applicable
^b Smoking history: 1: lifelong non-smoker; 2: current smoker; 3. Current reformed smoker (for> 15 years); 4. Current reformed smoker (for≤15 years); 5. Current reformed smoker (duration not specified)

ISSN: 1471-2407