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Table 1 Clinical–pathologic characteristics of the 22 nonsquamous lung carcinoma patients evaluated in this study

From: Functions and clinical significance of KLRG1 in the development of lung adenocarcinoma and immunotherapy

 

N (%)

N

22

Age, median (range)

58 (42–79)

Sex

 Male

7 (32%)

 Female

15 (68%)

Previous lines

 0

4 (18%)

 1

8 (37%)

 2

6 (27%)

  ≥ 3

4(18%)

Biopsy

 Archival

10 (45%)

 Baseline

12 (55%)

Drug response

 CR

1 (5%)

 PR

5 (22%)

 SD

7 (32%)

 PD

9 (41%)

Smoking

 Current smoker

8 (36%)

 Former smoker

11 (50%)

 Never smoker

3 (14%)

ECOG

 0

5 (23%)

 1

17 (77%)

Drug

 Nivolumab

14 (64%)

 Pembrolizumab

8 (36%)

PFS, median

3.03

Lung cancer EGFR status

 EGFR mutated

1 (5%)

 EGFR wild-type

21 (95%)

Lung cancer ALK status

 ALK rearranged

0 (0%)

 ALK not rearranged

21 (95%)

 NA

1 (5%)

  1. Abbreviations: CR complete response, PR partial response, SD stable disease, PD progression disease, PFS progression-free survival, ALK anaplastic lymphoma kinase, NA not applicable