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Fig. 6 | BMC Cancer

Fig. 6

From: miR-29a-3p inhibits endometrial cancer cell proliferation, migration and invasion by targeting VEGFA/CD C42/PAK1

Fig. 6

miR-29a-3p suppressed EC cells proliferation, colony formation, migration and invasion by inhibiting CDC42/PAK1 signaling pathway activity via targeting VEGFA. A VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on EC cells proliferation. B VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on EC cells colony ability. C VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on EC cells migration. D VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on EC cells invasion. E VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on CDC42/PAK1 signaling pathway activity. * P < 0.05, ** P < 0.01 and *** P < 0.001

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