Fig. 6
![Fig. 6](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12885-021-08506-z/MediaObjects/12885_2021_8506_Fig6_HTML.png)
miR-29a-3p suppressed EC cells proliferation, colony formation, migration and invasion by inhibiting CDC42/PAK1 signaling pathway activity via targeting VEGFA. A VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on EC cells proliferation. B VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on EC cells colony ability. C VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on EC cells migration. D VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on EC cells invasion. E VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on CDC42/PAK1 signaling pathway activity. * P < 0.05, ** P < 0.01 and *** P < 0.001