Table 3 Univariate and multivariate cox analysis for overall survival analysis

Marital status

Married

Separated

1.2

1.05–1.37

0.009

1.19

1.04–1.37

0.011

Single

1.17

1.02–1.35

0.024

1.24

1.07–1.43

0.003

Age

< 65

65–75

1.16

1.02–1.32

0.028

1.27

1.11–1.46

< 0.001

> 75

1.71

1.45–2.02

< 0.001

1.87

1.57–2.22

< 0.001

Race

Other

–

White

1.55

1.34–1.79

< 0.001

1.67

1.43–1.94

< 0.001

Black

1.71

1.41–2.09

< 0.001

1.77

1.45–2.18

< 0.001

Sex

female

male

0.97

0.86–1.11

0.677

Histological grade

Well differentiated

Moderately differentiated

1.23

1.01–1.5

0.038

1.21

0.99–1.47

0.062

Poorly differentiated

1.67

1.26–2.2

< 0.001

1.64

1.24–2.17

0.001

Undifferentiated

24.42

7.76–76.9

< 0.001

29.55

9.22–94.66

< 0.001

unknown

1.2

1.01–1.41

0.033

1.32

1.12–1.56

0.001

T

T1a

T1b

1.36

1.13–1.63

0.001

1.07

0.88–1.32

0.495

T2

1.67

1.38–2.03

< 0.001

1.32

1.07–1.63

0.010

T3

2.86

2.11–3.88

< 0.001

1.53

1.09–2.16

0.014

T4

4.91

3.47–6.95

< 0.001

2.77

1.90–4.03

< 0.001

N

N0

N1

1.42

0.92–2.18

0.115

M

M0

M1

2.5

1.67–3.74

< 0.001

1.67

1.09–2.55

0.019

Radiation therapy

Unradiation

Radiation

1.77

1.32–2.39

< 0.001

1.34

0.99–1.83

0.061

Chemotherapy

Unchemotherapy

chemotherapy

1.1

0.98–1.24

0.105

Tumor size

0-28 mm

28-35 mm

1.34

1.16–1.54

< 0.001

1.31

1.13–1.54

0.001

> 35 mm

1.85

1.63–2.1

< 0.001

1.64

1.41–1.90

< 0.001

Afp

nomal-afp

up-afp

1.28

1.13–1.45

< 0.001

1.26

1.11–1.43

< 0.001

Fibersis

non-fibersis

fibersis

1.03

0.81–1.3

0.821

unknown

1.11

0.89–1.4

0.35