Serum epidermal growth factor-like domain 7 serves as a novel diagnostic marker for early hepatocellular carcinoma

Table 2 Clinicopathological features for HCC patients in Testing and Validation Cohort

Clinicopathological features	Variables	Testing Cohort (n = 314)	Validation Cohort (n = 158)
Etiology	HBV	237	119
	HCV	0	0
	Non-B-non-C	77	39
Liver cirrhosis	Presence	239	125
Liver cirrhosis	Absence	75	33
Serum AFP level	≥ 20 μg/L	194	93
Serum AFP level	< 20 μg/L	120	65
Maximal tumor size	≤ 2 cm	61	22
Maximal tumor size	> 2 cm	253	136
Edmondson-Steiner grade	I – II	168	62
Edmondson-Steiner grade	III – IV	146	96
Capsular formation	Presence	173	77
Capsular formation	Absence	141	81
Tumor nodule number	Solitary	151	80
Tumor nodule number	Multiple (≤ 3)	163	78
BCLC stage	0	55	21
BCLC stage	A	259	137

HCC Hepatocellular carcinoma, HBV with hepatitis B virus infection, HCV with hepatitis C virus infection, Non-B-non-C without hepatitis B or hepatitis C virus infection, AFP α-fetoprotein

ISSN: 1471-2407