A novel immune-related gene pair prognostic signature for predicting overall survival in bladder cancer

BMC Cancer

Table 8 Gene sets enriched in low risk phenotype via KEGG

Gene set name	NES	NOM p-val	FDR q-val
KEGG_PEROXISOME	−1.986	< 0.001	1.467
KEGG_LINOLEIC_ACID_METABOLISM	−1.934	< 0.001	1.397
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION	−2.150	0.002	1.568
KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY	−2.070	0.004	1.419
KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY	−1.912	0.008	1.425
KEGG_AUTOIMMUNE_THYROID_DISEASE	−2.013	0.008	1.479
KEGG_GRAFT_VERSUS_HOST_DISEASE	−1.959	0.008	1.425
KEGG_ALLOGRAFT_REJECTION	−1.926	0.012	1.431
KEGG_PRIMARY_IMMUNODEFICIENCY	−1.777	0.028	1.053
KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	−1.678	0.030	0.943
KEGG_ETHER_LIPID_METABOLISM	−1.507	0.031	0.691
KEGG_AMINOACYL_TRNA_BIOSYNTHESIS	−1.645	0.036	0.895
KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION	−1.716	0.039	0.969

Gene sets with NOM p-val < 0.05 and FDR q-val < 0.25 are considered as significant
KEGG The Kyoto Encyclopedia of Genes and Genomes, NES normalized enrichment score, NOM nominal, FDR false discovery rate

ISSN: 1471-2407