A novel immune-related gene pair prognostic signature for predicting overall survival in bladder cancer

BMC Cancer

Table 7 Gene sets enriched in the high risk phenotype via KEGG

Gene set name	NES	NOM p-val	FDR q-val
KEGG_FOCAL_ADHESION	2.390	< 0.001	< 0.001
KEGG_ECM_RECEPTOR_INTERACTION	2.374	< 0.001	< 0.001
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	2.115	0.002	0.003
KEGG_GAP_JUNCTION	1.932	< 0.001	0.027
KEGG_CALCIUM_SIGNALING_PATHWAY	1.896	0.002	0.031
KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	1.860	0.006	0.035
KEGG_ADHERENS_JUNCTION	1.809	0.008	0.042
KEGG_MELANOGENESIS	1.763	< 0.001	0.057
KEGG_TGF_BETA_SIGNALING_PATHWAY	1.648	0.031	0.114
KEGG_PATHWAYS_IN_CANCER	1.633	0.017	0.118
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	1.625	0.017	0.119
KEGG_WNT_SIGNALING_PATHWAY	1.606	0.034	0.117
KEGG_MAPK_SIGNALING_PATHWAY	1.590	0.028	0.123
KEGG_GLYCOSAMINOGLYCAN_DEGRADATION	1.586	0.038	0.121
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION	1.572	0.041	0.126
KEGG_HEDGEHOG_SIGNALING_PATHWAY	1.568	0.030	0.124
KEGG_GNRH_SIGNALING_PATHWAY	1.537	0.028	0.137
KEGG_TIGHT_JUNCTION	1.522	0.039	0.138

Gene sets with NOM p-val < 0.05 and FDR q-val < 0.25 were considered significant
KEGG The Kyoto Encyclopedia of Genes and Genomes, NES normalized enrichment score, NOM nominal, FDR false discovery rate

ISSN: 1471-2407