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Table 7 Gene sets enriched in the high risk phenotype via KEGG

From: A novel immune-related gene pair prognostic signature for predicting overall survival in bladder cancer

Gene set name NES NOM p-val FDR q-val
KEGG_FOCAL_ADHESION 2.390 < 0.001 < 0.001
KEGG_ECM_RECEPTOR_INTERACTION 2.374 < 0.001 < 0.001
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 2.115 0.002 0.003
KEGG_GAP_JUNCTION 1.932 < 0.001 0.027
KEGG_CALCIUM_SIGNALING_PATHWAY 1.896 0.002 0.031
KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 1.860 0.006 0.035
KEGG_ADHERENS_JUNCTION 1.809 0.008 0.042
KEGG_MELANOGENESIS 1.763 < 0.001 0.057
KEGG_TGF_BETA_SIGNALING_PATHWAY 1.648 0.031 0.114
KEGG_PATHWAYS_IN_CANCER 1.633 0.017 0.118
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 1.625 0.017 0.119
KEGG_WNT_SIGNALING_PATHWAY 1.606 0.034 0.117
KEGG_MAPK_SIGNALING_PATHWAY 1.590 0.028 0.123
KEGG_GLYCOSAMINOGLYCAN_DEGRADATION 1.586 0.038 0.121
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION 1.572 0.041 0.126
KEGG_HEDGEHOG_SIGNALING_PATHWAY 1.568 0.030 0.124
KEGG_GNRH_SIGNALING_PATHWAY 1.537 0.028 0.137
KEGG_TIGHT_JUNCTION 1.522 0.039 0.138
  1. Gene sets with NOM p-val < 0.05 and FDR q-val < 0.25 were considered significant
  2. KEGG The Kyoto Encyclopedia of Genes and Genomes, NES normalized enrichment score, NOM nominal, FDR false discovery rate
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BMC Cancer

ISSN: 1471-2407

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