Fig. 13From: A novel immune-related gene pair prognostic signature for predicting overall survival in bladder cancerTMB. In the TCGA, the level of TMB was significantly negatively correlated with the risk score (A), and an increased level of TMB correlated with improved OS (P < 0.001) (B). These results were consistent with the results obtained from IMvigor210 (C-D). Moreover, in the IMvigor210 cohort, low-risk patients had more significant immunotherapy effects (PD-1 blockade therapy) (E). TMB, tumor mutation burden; TCGA, The Cancer Genome Atlas; OS, overall survival; CR, complete response, PR, partial response, SD, stable disease; PD, progressive diseaseBack to article page