Fig. 11

Immunological parameters and risk scores (TCGA). The expression levels of PD-1 (A), CTLA4 (B), and LAG3 (C) were significantly negatively correlated with the risk score. However, there was no significant difference between the risk score and other immune checkpoints, including PD-L1 (D), BTLA (E), and HAVCR2 (F). The stromal score (G) was significantly positively correlated with the risk score. There was no significant correlation between the immune score (H), tumor purity (I) and risk score. TCGA, The Cancer Genome Atlas; PD-1, programmed death-1; CTLA-4, cytotoxic T lymphocyte antigen-4; LAG3, lymphocyte activating 3; PD-L1, programmed death ligand-1; BTLA, B and T lymphocyte associated; HAVCR2, hepatitis A virus cellular receptor 2; BC, bladder cancer