Table 1 Characteristics of patients and tumors, preoperative laboratory tests, and follow-up

 Age (years)

54.5 ± 9.6

55.2 ± 10.0

53.9 ± 9.2

> 0.05

 Sex (male, %)

169 (79.7)

84 (80.8)

85 (78.7)

> 0.05

 Smoking (yes, %)

39 (18.4)

17 (16.3)

22 (20.4)

> 0.05

  No drinking

182 (85.8)

91 (87.5)

91 (84.3)

> 0.05

  Moderate drinking

21 (9.9)

9 (8.7)

12 (11.1)

  Heavy episodic drinking

9 (4.2)

4 (3.8)

5 (4.6)

 HBsAg (> 250 IU/mL, %)

167 (78.8)

74 (71.2)

93 (86.1)

< 0.01

 Positive HBeAg (n, %)

61 (28.8)

18 (17.3)

43 (39.8)

< 0.000

 Leukocyte (10⁹/L)

5.41 ± 1.83

5.44 ± 1.81

5.38 ± 1.86

> 0.05

 Hemoglobin (g/L)

145.0 ± 18.8

145.9 ± 19.2

144.1 ± 18.5

> 0.05

 Platelet (10⁹/L)

160.4 ± 70.1

166.8 ± 68.5

154.3 ± 71.4

> 0.05

 ALB (g/L)

40.2 ± 3.9

41.5 ± 3.5

38.8 ± 3.7

< 0.000

 ALT (U/L)

31 (22 - 46)

25 (18 - 33)

40 (28 - 54)

< 0.000

 AST (U/L)

32 (24 - 46)

26 (20 - 32)

40 (31 - 55)

< 0.000

 ALP (U/L)

92.4 ± 47.4

85.1 ± 43.1

99.5 ± 50.5

0.02

 GGT (U/L)

51 (32 - 98)

37 (23 - 60)

74 (44 - 123)

< 0.000

 PT (s)

13.9 ± 0.9

13.8 ± 1.0

13.9 ± 0.9

> 0.05

 INR

1.08 ± 0.08

1.07 ± 0.09

1.08 ± 0.08

> 0.05

 Creatinine (μmol/L)

67.44 ± 32.75

71.94 ± 44.76

63.1 ± 12.15

< 0.05

 AFP (ng/mL)

69.57 (6.38 - 1210.00)

23.09 (3.65 - 706.3)

145.50(11.25 - 1210.00)

< 0.01

 AFP < 10 ng/mL (n, %)

65 (30.7)

41 (39.4)

24 (22.2)

< 0.01

  Well (%)

39 (19.3)

22 (22.2)

17 (16.5)

> 0.05

  Moderate (%)

130 (64.4)

59 (59.6)

71 (68.9)

  Poor (%)

33 (16.3)

18 (18.2)

15 (14.6)

 Cirrhosis

167 (78.8)

78 (75.0)

89 (82.4)

> 0.05

 Diameter (< 5cm, %)

110 (51.9)

70 (67.3)

40 (37.0)

< 0.000

 Metastasis in the liver (yes, %)

24 (11.3)

10 (9.6)

14 (13)

> 0.05

 Capsule formation (yes, %)

130 (61.3)

55 (52.9)

75 (69.4)

< 0.05

 Tumor recurrence (n, %)

101 (47.6)

42 (40.4)

59 (54.6)

< 0.05

 AFP (ng/mL)

5.86 (2.77 - 195.68)

3.40 (2.18 -37.77)

16.12 (3.68 -671.05)

< 0.000

 AFP < 10 ng/mL (n, %)

120 (57.1)

71 (68.9)

49 (45.8)

< 0.000