Table 1 Target doses referred to 95% of the volume. For carbon ions, the biological dose is based on the LEM1 model using an alpha/beta of 2Gy. The biologically effective dose in 2 Gy fractions (BED2Gy) is calculated assuming an alpha/beta value of 3 Gy for ACC tissue
Experimental arm C12-only RT | Control arm Bimodal RT (photon IMRT & C12) | |||
|---|---|---|---|---|
CTV_basic | CTV_boost | CTV_basic | CTV_boost | |
Single dose | 3Gy(RBE) | 3Gy(RBE) | 2Gy | 3Gy(RBE) |
Total dose | 51Gy(RBE) | 15Gy(RBE) | 50Gy | 24Gy(RBE) |
BED2Gy | 61Gy | 18Gy | 50Gy | 29Gy |