Table 1 The Significant Change of SOCS Expression in Transcription Level between Different Types of Breast Cancer and Normal Breast Tissues
From: Comprehensive analysis of suppressor of cytokine signaling proteins in human breast Cancer
SOCS | Type of Breast Cancer versus Normal Breast Tissue | Fold Change | P Value | T Test | Source and/or Reference |
|---|---|---|---|---|---|
SOCS1 | Invasive Lobular Breast Carcinoma | 2.010 | 1.92E-10 | 7.108 | TCGA |
Invasive Breast Carcinoma | 2.076 | 1.19E-13 | 8.166 | TCGA | |
SOCS2 | Invasive Ductal Breast Carcinoma Stroma | −2.710 | 1.27E-6 | − 6.825 | Ma et al. |
Ductal Breast Carcinoma in Situ Epithelia | −2.203 | 0.001 | −3.456 | Ma et al. | |
Invasive Ductal Breast Carcinoma | −5.707 | 1.52E-46 | −20.589 | TCGA | |
Invasive Breast Carcinoma | − 4.347 | 3.49E-21 | − 11.498 | TCGA | |
Intraductal Cribriform Breast Adenocarcinoma | −8.398 | 0.008 | −6.596 | TCGA | |
Invasive Ductal Breast Carcinoma | −3.286 | 2.40E-82 | −29.894 | Curtis et al. | |
Medullary Breast Carcinoma | −2.479 | 4.50e-19 | −13.918 | Curtis et al. | |
Invasive Breast Carcinoma | −2.925 | 8.58E-7 | −6.462 | Curtis et al. | |
Breast Carcinoma | −3.007 | 3.18E-5 | −5.634 | Curtis et al. | |
Invasive Ductal Breast Carcinoma Stroma | −2.611 | 5.76E-4 | −4.293 | Karnoub et al. | |
Invasive Lobular Breast Carcinoma | −3.527 | 0.035 | −2.344 | Turashvili et al. | |
Invasive Breast Carcinoma | −4.560 | 0.002 | −6.624 | Gluck et al. | |
Ductal Breast Carcinoma | −6.257 | 1.14E-4 | −5.440 | Richardson et al. | |
SOCS3 | Invasive Ductal Breast Carcinoma Epithelia | 2.554 | 1.20E-4 | 4.474 | Ma et al. |
Invasive Breast Carcinoma Stroma | 3.056 | 8.40E-16 | 11.078 | Finak et al. | |
SOCS4 | Invasive Ductal Breast Carcinoma | 2.019 | 0.037 | 1.898 | Turashvili et al. |
SOCS5 | Invasive Ductal Breast Carcinoma Epithelia | 2.239 | 0.005 | 3.109 | Ma et al. |
SOCS6 | Invasive Lobular Breast Carcinoma | 3.099 | 0.016 | 2.593 | Radvanyi et al. |
SOCS7 | Invasive Ductal Breast Carcinoma | 2.415 | 1.85E-30 | 15.856 | TCGA |
Intraductal Cribriform Breast Adenocarcinoma | 2.599 | 4.85E-4 | 9.365 | TCGA | |
Invasive Breast Carcinoma | 2.047 | 5.37E-14 | 8.349 | TCGA | |
Mucinous Breast Carcinoma | 2.029 | 0.006 | 4.436 | TCGA |