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Table 1 The Significant Change of SOCS Expression in Transcription Level between Different Types of Breast Cancer and Normal Breast Tissues

From: Comprehensive analysis of suppressor of cytokine signaling proteins in human breast Cancer

SOCS Type of Breast Cancer versus Normal Breast Tissue Fold Change P Value T Test Source and/or Reference
SOCS1 Invasive Lobular Breast Carcinoma 2.010 1.92E-10 7.108 TCGA
Invasive Breast Carcinoma 2.076 1.19E-13 8.166 TCGA
SOCS2 Invasive Ductal Breast Carcinoma Stroma −2.710 1.27E-6 − 6.825 Ma et al.
Ductal Breast Carcinoma in Situ Epithelia −2.203 0.001 −3.456 Ma et al.
Invasive Ductal Breast Carcinoma −5.707 1.52E-46 −20.589 TCGA
Invasive Breast Carcinoma − 4.347 3.49E-21 − 11.498 TCGA
Intraductal Cribriform Breast Adenocarcinoma −8.398 0.008 −6.596 TCGA
Invasive Ductal Breast Carcinoma −3.286 2.40E-82 −29.894 Curtis et al.
Medullary Breast Carcinoma −2.479 4.50e-19 −13.918 Curtis et al.
Invasive Breast Carcinoma −2.925 8.58E-7 −6.462 Curtis et al.
Breast Carcinoma −3.007 3.18E-5 −5.634 Curtis et al.
Invasive Ductal Breast Carcinoma Stroma −2.611 5.76E-4 −4.293 Karnoub et al.
Invasive Lobular Breast Carcinoma −3.527 0.035 −2.344 Turashvili et al.
Invasive Breast Carcinoma −4.560 0.002 −6.624 Gluck et al.
Ductal Breast Carcinoma −6.257 1.14E-4 −5.440 Richardson et al.
SOCS3 Invasive Ductal Breast Carcinoma Epithelia 2.554 1.20E-4 4.474 Ma et al.
Invasive Breast Carcinoma Stroma 3.056 8.40E-16 11.078 Finak et al.
SOCS4 Invasive Ductal Breast Carcinoma 2.019 0.037 1.898 Turashvili et al.
SOCS5 Invasive Ductal Breast Carcinoma Epithelia 2.239 0.005 3.109 Ma et al.
SOCS6 Invasive Lobular Breast Carcinoma 3.099 0.016 2.593 Radvanyi et al.
SOCS7 Invasive Ductal Breast Carcinoma 2.415 1.85E-30 15.856 TCGA
Intraductal Cribriform Breast Adenocarcinoma 2.599 4.85E-4 9.365 TCGA
Invasive Breast Carcinoma 2.047 5.37E-14 8.349 TCGA
Mucinous Breast Carcinoma 2.029 0.006 4.436 TCGA