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Table 1 Baseline characteristics of HCC patients receiving anti-PD-1 blockades

From: Reductions in AFP and PIVKA-II can predict the efficiency of anti-PD-1 immunotherapy in HCC patients

Characteristics

Number (%)

Sample size

235

Age, years

  ≤ 50

109 (46.4)

 >50

126 (53.6)

Chronic liver disease

 HBV

203 (86.4)

 None

32 (13.6)

Gender

 Female

31 (13.2)

 Male

204 (86.8)

Vascular invasion

 No

113 (48.1)

 Yes

122 (51.9)

Extrahepatic metastasis

 No

148 (63.0)

 Yes

87 (37.0)

ALBI grade

 I

142 (60.4)

 II

93 (39.6)

AFP reduction> 50%

 No

122 (51.9)

 Yes

113 (48.1)

PIVKA-II reduction> 50%

 No

110 (46.8)

 Yes

125 (53.2)

Baseline AFP level, ng/ml

 Median (range)

2995.0 (25.14–121,000)

  ≤ 400

78 (33.2)

  > 400

157 (66.8)

Baseline PIVKA-II level, mAU/ml

 Median (range)

7209.0 (41–75,000)

  ≤ 400

44 (18.7)

  > 400

191 (81.3)