Variables | Univariate analysis | Multivariate analysis | ||||||
---|---|---|---|---|---|---|---|---|
Odds ratio | 95% C.I. | P-value | Odds ratio | 95% C.I. | P-value | |||
Preoperative factors | ||||||||
 Age: ≥80 vs < 80 (years) | 1.965 | 1.009 | 3.828 | 0.046 | 1.575 | 0.752 | 3.298 | 0.228 |
 BMI | 0.959 | 0.886 | 1.037 | 0.291 |  |  |  |  |
 Platelet count (104/uL) | 1.016 | 0.981 | 1.051 | 0.370 |  |  |  |  |
 Total Bilirubin (mg/dl) | 1.062 | 0.863 | 1.309 | 0.566 |  |  |  |  |
 PNI: <  50 vs ≥ 50 | 2.395 | 1.331 | 4.312 | 0.002 | 2.072 | 1.143 | 3.961 | 0.027 |
 AST (U/L) | 1.001 | 0.998 | 1.005 | 0.308 |  |  |  |  |
 ALT (U/L) | 1.003 | 0.998 | 1.009 | 0.183 |  |  |  |  |
 Prothrombin time (INR) | 1.106 | 0.184 | 6.623 | 0.912 |  |  |  |  |
 Total Cholesterol (mg/dL) | 1.001 | 0.995 | 1.006 | 0.717 |  |  |  |  |
 CRP (mg/dl) | 1.082 | 0.970 | 1.207 | 0.162 |  |  |  |  |
 Preoperative chemotherapy | 2.928 | 0.639 | 13.42 | 0.167 |  |  |  |  |
Tumor factor | ||||||||
 Morphology: Mass-forming vs the other type | 0.806 | 0.440 | 1.479 | 0.487 |  |  |  |  |
 Tumor size (cm) | 1.049 | 0.957 | 1.151 | 0.298 |  |  |  |  |
 Multi-nodular | 1.382 | 0.724 | 2.637 | 0.326 |  |  |  |  |
 Localization: Hilar vs Peripheral | 2.523 | 1.151 | 5.530 | 0.020 | 2.548 | 1.143 | 5.683 | 0.022 |
 CEA (ng/ml) | 1.003 | 0.992 | 1.013 | 0.608 |  |  |  |  |
 CA19–9 (U/ml) | 1.000 | 0.999 | 1.000 | 0.827 |  |  |  |  |
 Vascular invasion* | 1.172 | 0.680 | 2.020 | 0.566 |  |  |  |  |
 Lymph node metastasis | 1.122 | 0.579 | 2.171 | 0.732 |  |  |  |  |
 Tumor differentiation: mod/por vs well | 1.662 | 0.889 | 3.111 | 0.112 |  |  |  |  |
Operative factors | ||||||||
 Major hepatectomy vs Minor hepatectomy | 1.570 | 0.832 | 2.962 | 0.153 |  |  |  |  |
 Lymph node dissection | 1.254 | 0.686 | 2.294 | 0.460 |  |  |  |  |
 Bile duct resection | 3.456 | 1.948 | 6.129 | 0.001 | 1.135 | 0.491 | 2.625 | 0.767 |
 Vascular reconstruction** | 2.473 | 1.030 | 5.937 | 0.042 | 1.061 | 0.393 | 2.870 | 0.906 |
 Blood loss (ml) | 1.001 | 1.000 | 1.001 | 0.032 | 1.000 | 0.999 | 1.000 | 0.612 |
 Operation time (min) | 1.004 | 1.002 | 1.006 | 0.001 | 1.003 | 1.000 | 1.006 | 0.026 |