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Table 4 Logistic regression analysis to examine risk factors for major postoperative complications

From: Preoperative prognostic nutritional index predicts postoperative infectious complications and oncological outcomes after hepatectomy in intrahepatic cholangiocarcinoma

Variables

Univariate analysis

Multivariate analysis

Odds ratio

95% C.I.

P-value

Odds ratio

95% C.I.

P-value

Preoperative factors

 Age: ≥80 vs < 80 (years)

1.965

1.009

3.828

0.046

1.575

0.752

3.298

0.228

 BMI

0.959

0.886

1.037

0.291

    

 Platelet count (104/uL)

1.016

0.981

1.051

0.370

    

 Total Bilirubin (mg/dl)

1.062

0.863

1.309

0.566

    

 PNI: <  50 vs ≥ 50

2.395

1.331

4.312

0.002

2.072

1.143

3.961

0.027

 AST (U/L)

1.001

0.998

1.005

0.308

    

 ALT (U/L)

1.003

0.998

1.009

0.183

    

 Prothrombin time (INR)

1.106

0.184

6.623

0.912

    

 Total Cholesterol (mg/dL)

1.001

0.995

1.006

0.717

    

 CRP (mg/dl)

1.082

0.970

1.207

0.162

    

 Preoperative chemotherapy

2.928

0.639

13.42

0.167

    

Tumor factor

 Morphology: Mass-forming vs the other type

0.806

0.440

1.479

0.487

    

 Tumor size (cm)

1.049

0.957

1.151

0.298

    

 Multi-nodular

1.382

0.724

2.637

0.326

    

 Localization: Hilar vs Peripheral

2.523

1.151

5.530

0.020

2.548

1.143

5.683

0.022

 CEA (ng/ml)

1.003

0.992

1.013

0.608

    

 CA19–9 (U/ml)

1.000

0.999

1.000

0.827

    

 Vascular invasion*

1.172

0.680

2.020

0.566

    

 Lymph node metastasis

1.122

0.579

2.171

0.732

    

 Tumor differentiation: mod/por vs well

1.662

0.889

3.111

0.112

    

Operative factors

 Major hepatectomy vs Minor hepatectomy

1.570

0.832

2.962

0.153

    

 Lymph node dissection

1.254

0.686

2.294

0.460

    

 Bile duct resection

3.456

1.948

6.129

0.001

1.135

0.491

2.625

0.767

 Vascular reconstruction**

2.473

1.030

5.937

0.042

1.061

0.393

2.870

0.906

 Blood loss (ml)

1.001

1.000

1.001

0.032

1.000

0.999

1.000

0.612

 Operation time (min)

1.004

1.002

1.006

0.001

1.003

1.000

1.006

0.026

  1. *vascular invasion: pathologically diagnosed as invasion to portal vein, hepatic artery, hepatic vein, and inferior vena cava
  2. **reconstruction including portal vein, hepatic artery, hepatic vein, and inferior vena cava